sulfo-Cyanine5.5 amine
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 173C0 | 1 mg | $125 | in stock | |
| 273C0 | 5 mg | $285 | in stock | |
| 473C0 | 25 mg |
$680
|
in stock | |
| 573C0 | 50 mg |
$1260
|
in stock | |
| 673C0 | 100 mg |
$1990
|
in stock |
sulfo-Cyanine5.5 is a water-soluble cyanine dye for far red / NIR applications such as in vivo imaging. The dye possesses four sulfonate groups, rendering it highly hydrophilic and water-soluble. As well as other cyanines, sulfo-Cyanine5.5 has an outstanding extinction coefficient that makes it a bright fluorescent label for the far-red region.
This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. The aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc.) and used in enzymatic transamination labeling.
Absorption and emission spectra of sulfo-Cyanine5.5 fluorophore
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Cyanine5 maleimide
Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.General properties
| Appearance: | dark blue solid |
| Molecular weight: | 1077.41 |
| CAS number: | 2183440-46-0 |
| Molecular formula: | C46H54K2N4O13S4 |
| IUPAC name: | (E)-4-[(2E,4E)-5-{5-[6-(6-Aminohexylamino)-6-oxohexyl]-3,3-dimethyl-10,12-bis(oxysulfonyl)-5-azatricyclo[7.4.0.02,6]trideca-1,4,6,8,10,12-hexaen-4-yl}-2,4-pentadienylidene]-3,3-dimethyl-5-methyl-5-azatricyclo[7.4.0.02,6]trideca-1,6,8,10,12-pentaene-10,12-disulfonic acid dipotassium salt |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 673 |
| ε, L⋅mol−1⋅cm−1: | 211000 |
| Emission maximum, nm: | 691 |
| Fluorescence quantum yield: | 0.21 |
| CF260: | 0.09 |
| CF280: | 0.11 |
Product citations
- Gao, W.; He, J.; Chen, L.; Meng, X.; Ma, Y.; Cheng, L.; Tu, K.; Gao, X.; Liu, C.; Zhang, M.; Fan, K.; Pang, D.-W.; Yan, X. Deciphering the Catalytic Mechanism of Superoxide Dismutase Activity of Carbon Dot Nanozyme. Nature Communications, 2023, 14(1), 160. doi: 10.1038/s41467-023-35828-2
- Shevchuk, A. I.; Svinko, V. O.; Smirnov, A. N.; Solovyeva, E. V. SERS Study of Cyanine Dyes: Optimization of Metal Core and Molecular Label Choice for Plasmonic Nanotags. Dyes and Pigments, 2023, 216, 111329. doi: 10.1016/j.dyepig.2023.111329.
- Wang, D.; Li, Y.; Deng, X.; Torre, M.; Zhang, Z.; Li, X.; Zhang, W.; Cullion, K.; Kohane, D. S.; Weldon, C. B. An Aptamer-Based Depot System for Sustained Release of Small Molecule Therapeutics. Nature Communications, 2023, 14(1), 2444. doi: 10.1038/s41467-023-37002-0
- Zha, H.; Xu, Z.; Xu, X.; Lu, X.; Shi, P.; Xiao, Y.; Tsai, H.-I.; Su, D.; Cheng, F.; Cheng, X.; Chen, H. PD-1 Cellular Nanovesicles Carrying Gemcitabine to Inhibit the Proliferation of Triple Negative Breast Cancer Cell. Pharmaceutics, 2022, 14(6), 1263. doi: 10.3390/pharmaceutics14061263
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