Coumarin 343 X carboxylic acid

Cat. # Quantity Price Lead time
12690 1 mg $110.00 in stock
22690 5 mg $210.00 in stock
42690 25 mg $410.00 in stock
52690 50 mg $695.00 in stock
62690 100 mg $1190.00 in stock

Coumarin 343 is a blue emitting fluorophore used as a laser dye. The fluorophore can serve as a FRET donor for FAM (fluorescein).

Absorption and emission spectra of Coumarin 343

Absorption and emission spectra of Coumarin 343

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Coumarin 343 X azide

Coumarin 343 is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by Click chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility, and provides spatial separation between the dye and the biomolecule.

General properties

Appearance: yellow crystals
Molecular weight: 398.45
CAS number: 946123-11-1
Molecular formula: C22H26N2O5
IUPAC name: 6-({4-Oxo-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1,5,7,9(17)-tetraen-5-yl}carbonylamino)hexanoic acid
Solubility: Well soluble in DMF, DMSO, moderately soluble in DCM, DCE, EtOAc, insoluble in diethyl ether.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 437
ε, L⋅mol−1⋅cm−1: 39000
Emission maximum, nm: 477
Fluorescence quantum yield: 0.63
CF260: 0.29
CF280: 0.24
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