Cyanine5.5 carboxylic acid

Cyanine5.5 Carboxylic acids

Cat. #	Quantity	Price	Lead time
17090	1 mg	$125	in stock
27090	5 mg	$260	in stock
47090	25 mg	$510	in stock
57090	50 mg	$895	in stock
67090	100 mg	$1490	in stock

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Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.

Pre-activated NHS ester for the labeling of amine groups is also available.

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Cy5.5 absorbance and emission spectra

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sulfo-Cyanine3 DBCO

sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water-soluble fluorophore sulfo-Cyanine3 for copper-free click chemistry.

sulfo-Cyanine5.5 is a far-red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. This is an amine derivative that is reactive toward electrophiles. It can also be used for enzymatic transamination labeling.

sulfo-Cyanine5.5 carboxylic acid

Water-soluble far-red fluorescent dye sulfo-Cyanine5.5 in the form of free non-activated carboxylic acid. The dye is useful for calibration and as a non-reactive control.

General properties

Appearance:	dark blue powder
Molecular weight:	619.23
CAS number:	1449661-34-0 (without anion), 1449612-07-0 (inner salt)
Molecular formula:	C₄₀H₄₃ClN₂O₂
IUPAC name:	1H-Benz[e]indolium, 2-[5-[3-(5-carboxypentyl)-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]-1,3-pentadien-1-yl]-1,1,3-trimethyl-
Solubility:	soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	684
ε, L⋅mol⁻¹⋅cm⁻¹:	198000
Emission maximum, nm:	710
Fluorescence quantum yield:	0.2
CF₂₆₀:	0.07
CF₂₈₀:	0.03

Product citations

Shik, A. V.; Sobolev, P. V.; Zubritskaya, Y. V.; Baytler, M. O.; Stepanova, I. A.; Chernyaev, A. P.; Borschegovskaya, P. Yu.; Zolotov, S. A.; Doroshenko, I. A.; Podrugina, T. A.; Bliznyuk, U. A.; Rodin, I. A.; Beklemishev, M. K. Rapid Testing of Irradiation Dose in Beef and Potatoes by Reaction-Based Optical Sensing Technique. Journal of Food Composition and Analysis, 2024, 127, 105946. doi: 10.1016/j.jfca.2023.105946
Anderson, C. F.; Wang, Q.; Stern, D.; Leonard, E. K.; Sun, B.; Fergie, K. J.; Choi, C.; Spangler, J. B.; Villano, J.; Pekosz, A.; Brayton, C. F.; Jia, H.; Cui, H. Supramolecular Filaments for Concurrent ACE2 Docking and Enzymatic Activity Silencing Enable Coronavirus Capture and Infection Prevention. Matter, 2023, 6(2), 583–604. doi: 10.1016/j.matt.2022.11.027
Shik, A.V.; Stepanova, I.A.; Doroshenko, I.A.; Podrugina, T.A.; Beklemishev, M.K. Carbocyanine-Based Optical Sensor Array for the Discrimination of Proteins and Rennet Samples Using Hypochlorite Oxidation. Sensors (Basel), 2023, 23(9), 4299. doi: 10.3390/s23094299
Lee, S.; Kim, D.; Kang, K.-K.; Sung, S.-E.; Choi, J.-H.; Sung, M.; Shin, C.-H.; Jeon, E.; Kim, D.; Kim, D.; Lee, S.; Kim, H.-K.; Kim, K. Toxicity and Biodistribution of Fragmented Polypropylene Microplastics in ICR Mice. International Journal of Molecular Sciences, 2023, 24(10), 8463. doi: 10.3390/ijms24108463

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Cy® is a trademark of GE Healthcare.

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.