Cyanine5.5 carboxylic acid

Cat. # Quantity Price Lead time
17090 1 mg $110.00 in stock
27090 5 mg $210.00 in stock
47090 25 mg $410.00 in stock
57090 50 mg $695.00 in stock
67090 100 mg $1190.00 in stock

Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.

Pre-activated NHS ester for the labeling of amine groups is also available.

Cy5.5 absorbance and emission spectra

Cy5.5 absorbance and emission spectra

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Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

General properties

Appearance: dark blue powder
Molecular weight: 619.23
CAS number: 1449661-34-0 (without anion), 1449612-07-0 (inner salt)
Molecular formula: C40H43ClN2O2
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​(5-​carboxypentyl)​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Francis, D.M. Manspeaker, M.P.; Archer, P.A.; Sestito, L.F.; Heiler, A.J.; Schudel, A.; Thomas, S.N. Drug-eluting immune checkpoint blockade antibody-nanoparticle conjugate enhances locoregional and systemic combination cancer immunotherapy through T lymphocyte targeting. Biomaterials, 2021, 279, 121184. doi: 10.1016/j.biomaterials.2021.121184
  2. Phung, C.D.; Le, T.G.; Nguyen, V.H.; Vu, T.T.; Nguyen, H.Q.; Kim, J.O.; Yong, C.S.; Nguyen, C.N. PEGylated-Paclitaxel and Dihydroartemisinin Nanoparticles for Simultaneously Delivering Paclitaxel and Dihydroartemisinin to Colorectal Cancer. Pharmaceutical Research, 2020, 37, 129. doi: 10.1007/s11095-020-02819-7
  3. Alfaifi, A.A.; Heyder, R.S.; Bielski, E.R.; Almuqbil, R.M.; Kavdia, M.; Gerk, P.M.; da Rocha, S.R.P. Megalin-targeting liposomes for placental drug delivery. Journal of Controlled Release, 2020, 324, 366–378. doi: 10.1016/j.jconrel.2020.05.033
  4. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
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