Cyanine5.5 carboxylic acid

Cat. # Quantity Price Lead time
17090 1 mg $125 in stock
27090 5 mg $260 in stock
47090 25 mg $510 in stock
57090 50 mg $895 in stock
67090 100 mg $1490 in stock
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Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.

Pre-activated NHS ester for the labeling of amine groups is also available.

Cy5.5 absorbance and emission spectra

Cy5.5 absorbance and emission spectra

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sulfo-Cyanine5 DBCO

Water soluble cycloalkyne for copper-free click chemistry reaction with azides. A derivative of sulfo-Cyanine5.

FAM amine, 5-isomer

Amino derivative of fluorescein, pure 5-isomer. Contains a linker arm between the aliphatic amine group, and the fluorophore. Useful for the labeling via enzymatic transamination, for the reactions with electrophilic reagents, and for reductive amination.

sulfo-Cyanine5 NHS ester

Water-soluble sulfo-Cyanine5 succinimidyl ester for labeling various amine-containing molecules in the aqueous phase.

General properties

Appearance: dark blue powder
Molecular weight: 619.23
CAS number: 1449661-34-0 (without anion), 1449612-07-0 (inner salt)
Molecular formula: C40H43ClN2O2
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​(5-​carboxypentyl)​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Shik, A. V.; Sobolev, P. V.; Zubritskaya, Y. V.; Baytler, M. O.; Stepanova, I. A.; Chernyaev, A. P.; Borschegovskaya, P. Yu.; Zolotov, S. A.; Doroshenko, I. A.; Podrugina, T. A.; Bliznyuk, U. A.; Rodin, I. A.; Beklemishev, M. K. Rapid Testing of Irradiation Dose in Beef and Potatoes by Reaction-Based Optical Sensing Technique. Journal of Food Composition and Analysis, 2024, 127, 105946. doi: 10.1016/j.jfca.2023.105946
  2. Anderson, C. F.; Wang, Q.; Stern, D.; Leonard, E. K.; Sun, B.; Fergie, K. J.; Choi, C.; Spangler, J. B.; Villano, J.; Pekosz, A.; Brayton, C. F.; Jia, H.; Cui, H. Supramolecular Filaments for Concurrent ACE2 Docking and Enzymatic Activity Silencing Enable Coronavirus Capture and Infection Prevention. Matter, 2023, 6(2), 583–604. doi: 10.1016/j.matt.2022.11.027
  3. Shik, A.V.; Stepanova, I.A.; Doroshenko, I.A.; Podrugina, T.A.; Beklemishev, M.K. Carbocyanine-Based Optical Sensor Array for the Discrimination of Proteins and Rennet Samples Using Hypochlorite Oxidation. Sensors (Basel), 2023, 23(9), 4299. doi: 10.3390/s23094299
  4. Lee, S.; Kim, D.; Kang, K.-K.; Sung, S.-E.; Choi, J.-H.; Sung, M.; Shin, C.-H.; Jeon, E.; Kim, D.; Kim, D.; Lee, S.; Kim, H.-K.; Kim, K. Toxicity and Biodistribution of Fragmented Polypropylene Microplastics in ICR Mice. International Journal of Molecular Sciences, 2023, 24(10), 8463. doi: 10.3390/ijms24108463
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