Cyanine5.5 carboxylic acid

Cat. # Quantity Price Lead time
17090 1 mg $110.00 in stock
27090 5 mg $210.00 in stock
47090 25 mg $410.00 in stock
57090 50 mg $695.00 in stock
67090 100 mg $1190.00 in stock

Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.

Pre-activated NHS ester for the labeling of amine groups is also available.

Cy5.5 absorbance and emission spectra

Cy5.5 absorbance and emission spectra

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General properties

Appearance: dark blue powder
Molecular weight: 619.23
CAS number: 1449661-34-0 (without anion), 1449612-07-0 (inner salt)
Molecular formula: C40H43ClN2O2
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​(5-​carboxypentyl)​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 209000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Zhang, L.; Yao, M.; Yan, W.; Liu, X.; Jiang, B.; Qian, Z.; Gao, Y.; Lu, X.-J.; Chen, X.; Wang, Q.-L. Delivery of a chemotherapeutic drug using novel hollow carbon spheres for esophageal cancer treatment. International Journal of Nanomedicine, 2017, 12, 6759–6769. doi: 10.2147/IJN.S142916
  2. Liu, M.; Richardson, R.R.; Mountford, S.J.; Zhang, L.; Tempone, M.H.; Herzog, H.; Holliday, N.D.; Thompson, P.E. Identification of a Cyanine-Dye Labelled Peptidic Ligand for Y1R and Y4R, based upon the Neuropeptide Y C-terminal analogue, BVD-15. Bioconjugate Chemistry, 2016, 27(9), 2166–2175. doi: 10.1021/acs.bioconjchem.6b00376
  3. Camerino, M.A.; Liu, M.; Moriya, S.; Kitahashi, T.; Mahgoub, A.; Mountford, S.J.; Chalmers, D.K.; Soga, T.; Parhar, I.S.; Thompson, P.E. Beta amino acid-modified and fluorescently labelled kisspeptin analogues with potent KISS1R activity. Journal of Peptide Science, 2016, 22(6), 406–414. doi: 10.1002/psc.2883
  4. Zhao, Y.; Fay, F.; Hak, S.; Manuel Perez-Aguilar, J.; Sanchez-Gaytan, B.L.; Goode, B.; Duivenvoorden, R.; de Lange Davies, C.; Bjørkøy, A.; Weinstein, H.; Fayad, Z.A.; Pérez-Medina, C.; Mulder, W.J.M. Augmenting drug-carrier compatibility improves tumour nanotherapy efficacy. Nature Communications, 2016, 7, 11221. doi: 10.1038/ncomms11221
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