sulfo-Cyanine3 alkyne

Cat. # Quantity Price Lead time
A13B0 1 mg $125 in stock
B13B0 5 mg $325 in stock
C13B0 10 mg $470 in stock
D13B0 25 mg $850 in stock
E13B0 50 mg $1490 in stock
F13B0 100 mg $1990 in stock
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A water-soluble alkyne dye for copper-catalyzed click chemistry, an analog of Cy3® alkyne.

sulfo-Cyanine3 is a fluorophore compatible with a wide range of fluorescent scanners, imagers, microscopes, and other instrumentation. It is a bright and photostable dye, which is also easily detected in gels by the naked eye in low amounts (<1 nmol).

Absorbance and emission spectra of sulfo-Cyanine3

Absorbance and emission spectra of sulfo-Cyanine3

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sulfo-Cyanine3 DBCO

sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water-soluble fluorophore sulfo-Cyanine3 for copper-free click chemistry.

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Copper(II)-THPTA catalytic buffer, 1.5x

Ready-to-use catalytic buffer containing сopper(II) and water-soluble THPTA ligand. It is suitable for click chemistry modification of proteins.

General properties

Appearance: dark red powder
Mass spec M+ increment: 653.2
Molecular weight: 691.90
CAS number: 2055138-87-7 (inner salt); 2055138-88-8 (sodium salt)
Molecular formula: C33H38KN3O7S2
Solubility: soluble in water (0.57 M = 40 g/L), DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

Product citations

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
  2. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a "multiple gear" regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  3. Guarin, M.; Ny, A.; De Croze, N.; Maes, J.; Léonard, M.; Annaert, P.; de Witte, P. A. M. Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals, 2021, 14(6), 576. doi: 10.3390/ph14060576
  4. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration. Scientific Reports, 2021, 11, 12229. doi: 10.1038/s41598-021-91612-6
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