THPTA ligand
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| F4050 | 100 mg | $65.00 | in stock | |
| H4050 | 500 mg | $199.00 | in stock | |
| I4050 | 1 g | $369.00 | 5 days | |
| K4050 | 5 g |
$1568.00
|
in stock |
THPTA ligand (tris-hydroxypropyltriazolylmethylamine) is a triazole ligand for water-based copper-catalyzed click chemistry reactions. This reagent is very well water-soluble. It is especially useful for click chemistry labeling and conjugation of proteins, including antibodies, when organic co-solvents are undesirable.
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| Appearance: | off white solid |
| Molecular weight: | 434.5 |
| CAS number: | 760952-88-3 |
| Molecular formula: | C18H30N10O3 |
| IUPAC name: | 3-[4-[[bis[[1-(3-hydroxypropyl)triazol-4-yl]methyl]amino]methyl]triazol-1-yl]propan-1-ol |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. |
| MSDS: | Download |
| Product specifications |
Product citations
- Soxpollard, N.; Strauss, S.; Jungmann, R.; MacPherson, I. Selection of Antibody-Binding Covalent Aptamers. bioRxiv, 2023, preprint. doi: 10.1101/2023.03.09.530504
- Salazar-Chaparro, A. F.; Halder, S.; Trader, D. J. Synthesis and Application of a Clickable Epoxomicin-Based Probe for Proteasome Activity Analysis. Current Protocols, 2022, 2(7), e490. doi: 10.1002/cpz1.490
- Rudack, T.; Teuber, C.; Scherlo, M.; Güldenhaupt, J.; Schartner, J.; Lübben, M.; Klare, J.P.; Gerwert, K.; Kötting, C. The Ras Dimer Structure. Chemical Science, 2021, 12(23), 8178-8189. doi: 10.1039/d1sc00957e
- Wilder, L.M. Handali, P.R.; Webb, L.J.; Crooks, R.M. Interactions between Oligoethylene Glycol-Capped AuNPs and Attached Peptides Control Peptide Structure. Bioconjugate Chemistry, 2020, 31(10), 2383–2391. doi: 10.1021/acs.bioconjchem.0c00447
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