THPTA ligand
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| F4050 | 100 mg | $65 | in stock | |
| H4050 | 500 mg | $199 | in stock | |
| I4050 | 1 g | $369 | in stock | |
| K4050 | 5 g |
$1568
|
in stock |
THPTA ligand (tris-hydroxypropyltriazolylmethylamine) is a triazole ligand for water-based copper-catalyzed click chemistry reactions. This reagent is very well water-soluble. It is especially useful for click chemistry labeling and conjugation of proteins, including antibodies, when organic co-solvents are undesirable.
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| Appearance: | off white solid |
| Molecular weight: | 434.5 |
| CAS number: | 760952-88-3 |
| Molecular formula: | C18H30N10O3 |
| IUPAC name: | 3-[4-[[bis[[1-(3-hydroxypropyl)triazol-4-yl]methyl]amino]methyl]triazol-1-yl]propan-1-ol |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. |
| MSDS: | Download |
| Product specifications |
Product citations
- Slapak, E.J.; el Mandili, M.; Ten Brink, M.S.; Kros, A.; Bijlsma, M.F.; Spek, C.A. CAPN2-responsive mesoporous silica nanoparticles: A promising nanocarrier for targeted therapy of pancreatic cancer. Cancer Letters, 2024, 590, 216845. doi: 10.1016/j.canlet.2024.216845
- Narum, S.; Deal, B.; Ogasawara, H.; Mancuso, J. N.; Zhang, J.; Salaita, K. An Endosomal Escape Trojan Horse Platform to Improve Cytosolic Delivery of Nucleic Acids. ACS Nano, 2024, 18(8), 6186–6201. doi: 10.1021/acsnano.3c09027
- Cardenas, A. J.; Thomas, K. S.; Broden, M. W.; Ferraro, N. J.; Pires, M. M.; John, C. M.; Jarvis, G. A.; Criss, A. K. Neisseria Gonorrhoeae Scavenges Host Sialic Acid for Siglec-Mediated, Complement-Independent Suppression of Neutrophil Activation. mBio, 2024, 15(5), e00119-24. doi: 10.1128/mbio.00119-24
- Soxpollard, N.; Strauss, S.; Jungmann, R.; MacPherson, I. S. Selection of Antibody-Binding Covalent Aptamers. Commun Chem, 2024, 7(1), 1-11. doi: 10.1038/s42004-024-01255-7
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