Cyanine7 maleimide

Cat. # Quantity Price Lead time
15080 1 mg $125 in stock
25080 5 mg $260 in stock
45080 25 mg $510 in stock
55080 50 mg $895 in stock
65080 100 mg $1490 in stock
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Near-infrared, sulfhydryl reactive Cyanine7 dye, an analog of Cy7® maleimide.

This reagent allows to attach near infrared Cyanine7 dye to proteins with free sulfhydryl groups. Labeled proteins thus obtained are used in NIR bioimaging applications. NIR imaging systems can be used to visualize distribution of labeled proteins in tissues even in live organism.

Cyanine7 absorbance and emission spectra

Cyanine7 absorbance and emission spectra

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General properties

Appearance: green powder
Molecular weight: 707.34
CAS number: 2120392-49-4 (without anion)
Molecular formula: C43H51ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

Product citations

  1. Mitin, D. E.; Chubarov, A. S. Fluorinated Human Serum Albumin as Potential 19F Magnetic Resonance Imaging Probe. Molecules, 2023, 28(4), 1695. doi: 10.3390/molecules28041695.
  2. Feng, Y.; Lee, J.; Yang, L.; Hilton, M.B.; Morris, K.; Seaman, S.; Edupuganti, V.V.S.R.; Hsu, K.-S.; Dower, C.; Yu, G.; So, D.; Bajgain, P.; Zhu, Z.; Dimitrov, D.S.; Patel, N.L.; Robinson, C.M.; Difilippantonio, S.; Dyba, M.; Corbel, A.; Basuli, F.; Swenson, R.E.; Kalen, J.D.; Suthe, S.R.; Hussain, M.; Italia, J.S.; Souders, C.A.; Gao, L.; Schnermann, M.J.; St. Croix, B. Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability. Cell Reports, 2023, 42(12), 113503. doi: 10.1016/j.celrep.2023.113503
  3. Mitin, D.E.; Chubarov, A.S. Fluorinated Human Serum Albumin as Potential 19 F Magnetic Resonance Imaging Probe. Molecules, 2023, 28(4), 1695. doi: 10.3390/molecules28041695
  4. Peplau, E.; De Rose, F.; Eichinger, A.; Reder, S.; Mittelhäuser, M.; Scafetta, G.; Schwaiger, M.; Weber, W. A.; Bartolazzi, A.; D’Alessandria, C.; Skerra, A. Effective Rational Humanization of a PASylated Anti-Galectin-3 Fab for the Sensitive PET Imaging of Thyroid Cancer in Vivo. Sci Rep, 2021, 11(1), 7358. doi: 10.1038/s41598-021-86641-0
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