Cyanine7 maleimide

Cat. # Quantity Price Lead time
15080 1 mg $110.00 in stock
25080 5 mg $210.00 in stock
45080 25 mg $410.00 in stock
55080 50 mg $695.00 in stock
65080 100 mg $1190.00 in stock

Near-infrared, sulfhydryl reactive Cyanine7 dye, an analog of Cy7® maleimide.

This reagent allows to attach near infrared Cyanine7 dye to proteins with free sulfhydryl groups. Labeled proteins thus obtained are used in NIR bioimaging applications. NIR imaging systems can be used to visualize distribution of labeled proteins in tissues even in live organism.

Cyanine7 absorbance and emission spectra

Cyanine7 absorbance and emission spectra

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General properties

Appearance: green powder
Molecular weight: 707.34
Molecular formula: C43H51ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download

Spectral properties

Excitation maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

Product citations

  1. Melgar-Asensio, I.; Kandela, I.; Aird, F.; Darjatmoko, S.R.; de Los Rios, C.; Sorenson, C.M.; Albert, D.M.; Sheibani, N.; Henkin, J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Investigative Ophthalmology & Visual Science, 2018, 59(10), 4071–4081. doi: 10.1167/iovs.18-24087
  2. Matsuoka, D.; Watanabe, H.; Shimizu, Y.; Kimura, H.; Yagi, Y.; Kawai, R.; Ono, M.; Saji, H. Structure–activity relationships of succinimidyl-Cys-C (O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2291–2301. doi: 10.1016/j.bmc.2018.03.015
  3. Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; Pietzsch, J. In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide-Oligosaccharide Interaction in Immunocompetent Nude Mice. In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide-Oligosaccharide Interaction in Immunocompetent Nude Mice, 2017, 27(15), 1605189. doi: 10.1002/adfm.201605189
  4. Wang, T.; Tang, Y.; He, X.; Yan, J.; Wang, C.; Feng, X. Self-Assembled Raspberry-Like Core/Satellite Nanoparticles for Anti-Inflammatory Protein Delivery. ACS Applied Materials & Interfaces, 2017, 9(8), 6902–6907. doi: 10.1021/acsami.6b16277
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