Cyanine5 amine

Cat. # Quantity Price Lead time
130C0 1 mg $110.00 in stock
230C0 5 mg $210.00 in stock
430C0 25 mg $410.00 in stock
530C0 50 mg $695.00 in stock
630C0 100 mg $1190.00 in stock
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Cyanine5 amine is a reactive dye which contains amino group, an analog of Cy5® amine. This reagent can be coupled with a variety of activated esters and other electrophilic reagents. For example, this amine can be coupled with EDC-activated carboxylic groups.

This bright and photostable dye is suitable for many different methods of fluorescence detection. Colorful fluorophore can also be easily detected in small quantities (nanomols) by naked human eye.

Cyanine5 amine absorbance and emission spectra

Cyanine5 amine absorbance and emission spectra

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General properties

Appearance: dark blue powder
Molecular weight: 653.77
CAS number: 1807529-70-9 (Cl-), 1807589-58-7
Molecular formula: C38H54Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download

Spectral properties

Excitation maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

Product citations

  1. Kongkatigumjorn, N.; Smith, S.A.; Chen, M.Z.; Fang, K.; Yang, S.; Gillies, E.R.; Johnston, A.P.R.; Such, G.K. Controlling Endosomal Escape Using pH Responsive Nanoparticles with Tunable Disassembly. Applied Nano Materials, in press. doi: 10.1021/acsanm.8b00338
  2. Nuhn, L.; Van Hoecke, L.; Deswarte, K.; Schepens, B.; Li, Y.; Lambrecht, B.N.; De Koker, S.; David, S.A.; Saelens, X.; De Geest, B.G. Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist. Biomaterials, in press. doi: 10.1016/j.biomaterials.2018.03.026
  3. Wang, B.; Chen, G.; Urabe, G.; Xie, R.; Wang, Y.; Shi, X.; Guo, L.-W.; Gong, S.; Kent, K.C. A paradigm of endothelium-protective and stent-free anti-restenotic therapy using biomimetic nanoclusters. Biomaterials, 2018, 178, 293–301. doi: 10.1016/j.biomaterials.2018.06.025
  4. Shih, T.-Y.; Blacklow, S.O.; Li, A.W.; Freedman, B.R.; Bencherif, S.; Koshy, S.T.; Darnell, M.C.; Mooney, D.J. Injectable, Tough Alginate Cryogels as Cancer Vaccines. Advanced Healthcare Materials, 2018, 7(10), 1701469. doi: 10.1002/adhm.201701469
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