AmdU (5-Azidomethyl-2'-deoxyuridine)

Cat. # Quantity Price Lead time
B1540 5 mg $120 in stock
D1540 25 mg $255 in stock
F1540 100 mg $890 in stock
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Azidomethyl-dU (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similar to EdU.

In contrast to EdU which needs to be further modified with azides in the presence of the copper catalyst, AmdU can also react in the absence of copper catalyst using SPAAC click chemistry with strained cycloalkynes, such as cyclooctynes. This enables the detection of nascent DNA in benign, copper-free conditions.

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General properties

Appearance: white / off white solid
Molecular weight: 283.24
CAS number: 59090-48-1
Molecular formula: C10H13N5O5
IUPAC name: 5-Azidomethyl-2'-deoxyuridine
Solubility: in water, alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
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