Cyanine7.5 maleimide

Cyanine7.5 Maleimides Near infrared (NIR) imaging
Cat. # Quantity Price Lead time
16080 1 mg $110.00 in stock
26080 5 mg $210.00 in stock
46080 25 mg $410.00 in stock
56080 50 mg $695.00 in stock
66080 100 mg $1190.00 in stock
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Thiol-reactive, near infrared dye Cyanine7.5 for the labeling of protein SH groups, an analog of Cy7.5® maleimide.

Most proteins contain sulfhydryl groups which can be selectively labeled with maleimides. With this reagent, these proteins can be converted to near infrared (NIR) fluorescent conjugates. After it, the conjugates can be used in non-invasive live organism imaging to study distribution of the protein in tissues and organs.

Cy7.5 maleimide structure
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Cyanine7.5 absorbance and emission spectra

Cyanine7.5 absorbance and emission spectra

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Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

General properties

Appearance: green powder
Molecular weight: 807.46
Molecular formula: C51H55ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808

Product citations

  1. Men, Y.; Peng, S.; Yang, P.; Jiang, Q.; Zhang, Y.; Shen, B.; Dong, P.; Pang, Z.; Yang, W. Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23509–23521. doi: 10.1021/acsami.8b03943
Cy® is a trademark of GE Healthcare.
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