sulfo-Cyanine3 maleimide

Cat. # Quantity Price Lead time
11380 1 mg $115 in stock
21380 5 mg $290 in stock
41380 25 mg $695 in stock
51380 50 mg $1190 in stock
61380 100 mg $1990 in stock
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sulfo-Cyanine3 maleimide is a water-soluble, thiol-reactive dye for labeling. This is an analog of Cy3® maleimide.

This product is recommended for labeling antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require organic co-solvent.

A non-sulfonated Cyanine3 maleimide is available.

Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide

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sulfo-Cyanine5 NHS ester

Water-soluble sulfo-Cyanine5 succinimidyl ester for labeling various amine-containing molecules in the aqueous phase.

General properties

Appearance: red powder
Molecular weight: 776.96
CAS number: 1656990-68-9
Molecular formula: C36H41KN4O9S2
IUPAC name: 3H-​Indolium, 2-​[3-​[1-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene]​-​1-​propen-​1-​yl]​-​1,​3,​3-​trimethyl-​5-​sulfo-​, inner salt, potassium salt
Solubility: soluble in water (0.39 M = 30 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

Product citations

  1. Damm, A.; Paik, S.-J.; Sadhu, R.K.; Di-Cicco, A.; Manzi, J.; Castellana, M.; Margeat, E.; Dahan, M.; Sens, P.; Lévy, D.; Bassereau, P. Mechanosensitivity of an ABC Membrane Transporter Revealed by Single Molecule FRET and Activity Measurement. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.24.577054
  2. Proksch, J.; Dal Colle, M.C.S.; Heinz, F.; Schmidt, R.F.; Gottwald, J.; Delbianco, M.; Keller, B.G.; Gradzielski, M.; Alexiev, U.; Koksch, B. Impact of glycan nature on structure and viscoelastic properties of glycopeptide hydrogels. ChemRxiv, 2024, preprint. doi: 10.26434/chemrxiv-2024-wzm4c
  3. Moochickal Assainar, B.; Ragunathan, K.; Baldridge, R.D. Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD. Nature Communications, 2024, 15, 1340. doi: 10.1038/s41467-024-45541-3
  4. Williams, C.; Dong, K. C.; Arkinson, C.; Martin, A. The Ufd1 Cofactor Determines the Linkage Specificity of Polyubiquitin Chain Engagement by the AAA+ ATPase Cdc48. Molecular Cell, 2023, 83(5), 759-769.e7. doi: 10.1016/j.molcel.2023.01.016
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