Cyanine5.5 azide

Cat. # Quantity Price Lead time
14030 100 uL, 10 mM/DMSO $110.00 in stock
34030 500 uL, 10 mM/DMSO $210.00 in stock
44030 1 mL, 10 mM/DMSO $410.00 in stock
A4030 1 mg $110.00 in stock
B4030 5 mg $210.00 in stock
C4030 10 mg $310.00 in stock
D4030 25 mg $410.00 in stock
E4030 50 mg $695.00 in stock

This Cyanine5.5 labeling reagent is a dye azide for Click Chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5®, Alexa Fluor 680, and DyLight 680.

Cy5.5 absorbance and emission spectra

Cy5.5 absorbance and emission spectra

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Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

General properties

Appearance: dark blue powder / solution
Molecular weight: 701.34
Molecular formula: C43H49ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 209000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Zhang, H.; Wu, J.; Wu, J.; Fan, Q.; Zhou, J.; Wu, J.; Liu, S.; Zang, J.; Ye, J.; Xiao, M.; Tian, T.; Gao, J. Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice. Journal of Nanobiotechnology, 2019, 17, 29. doi: 10.1186/s12951-019-0461-7
  2. Sun, H.; Yan, L.; Carter, K.A.; Zhang, J.; Caserto, J.; Lovell, J.F.; Wu, Y.; Cheng, C. Zwitterionic Crosslinked Biodegradable Nanocapsules for Cancer Imaging. Langmuir, 2019, 35(5), 1440–1449. doi: 10.1021/acs.langmuir.8b01633
  3. Stefaniak, J.; Lewis, A.M.; Conole, D.; Galan, S.R.G.; Bataille, C.J.R.; Wynne, G.M.; Castaldi, M.P.; Lundbäck, T.; Russell, A.J.; Huber, K.V.M. Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors. ACS Chemical Biology, 2018, 13(10), 2849–2854. doi: 10.1021/acschembio.8b00665
  4. Tian, T.; Zhang, H.-X.; He, C.-P.; Fan, S.; Zhu, Y.-L.; Qi, C.; Huang, N.-P.; Xiao, Z.-D.; Lu, Z.-H.; Tannous, B.A.; Gao, J. Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy. Biomaterials, 2018, 150, 137–149. doi: 10.1016/j.biomaterials.2017.10.012
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