Cyanine5.5 azide

Cyanine5.5 Azides Click chemistry
Cat. # Quantity Price Lead time
14030 100 uL, 10 mM/DMSO
– 
in stock
34030 500 uL, 10 mM/DMSO
$199
 in stock
44030 1 mL, 10 mM/DMSO
$495
 in stock
A4030 1 mg
– 
in stock
B4030 5 mg
$199
 in stock
C4030 10 mg
$297
 in stock
D4030 25 mg
$495
 in stock
E4030 50 mg
$895
 in stock
F4030 100 mg
$1490
 in stock
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This Cyanine5.5 labeling reagent is a dye azide for click chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5® and DyLight 680.

Cyanine5.5 azide, azide stock solution for click chemistry (10 mM in DMSO), 44030
Cyanine5.5 azide, azide stock solution for click chemistry (10 mM in DMSO), 44030
Cyanine5.5 azide, D4030
Cyanine5.5 azide, D4030
Structure of Cyanine5.5 azide
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Absorbance and emission spectra of Cyanine5.5

Absorbance and emission spectra of Cyanine5.5

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Sulfonated Cyanine5 amine derivative for the conjugation with electrophiles and enzymatic transamination labeling.

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General properties

Appearance: dark violet solid/ dark blue solution
Molecular weight: 701.34
Molecular formula: C43H49ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (1.6 uM, 1.2 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Kodaka, M.; Kikuchi, A.; Kawahira, K.; Kamada, H.; Katsuta, R.; Ishigami, K.; Suzuki, T.; Yamamoto, Y.; Inoue, J. Identification of a novel target of sulforaphane: Sulforaphane binds to acyl-protein thioesterase 2 (APT2) and attenuates its palmitoylation. Biochemical and biophysical research communications, 2024, 726, 150244. doi: 10.1016/j.bbrc.2024.150244
  2. Kang, J.‐Y.; Mun, D.; Chun, Y.; Park, D.‐S.; Kim, H.; Yun, N.; Joung, B. Engineered small extracellular vesicle‑mediated NOX4 siRNA delivery for targeted therapy of cardiac hypertrophy. Journal of Extracellular Vesicles, 2023, 12(10), 12371. doi: 10.1002/jev2.12371
  3. Bashore, C.; Prakash, S.; Johnson, M. C.; Conrad, R. J.; Kekessie, I. A.; Scales, S. J.; Ishisoko, N.; Kleinheinz, T.; Liu, P. S.; Popovych, N.; Wecksler, A. T.; Zhou, L.; Tam, C.; Zilberleyb, I.; Srinivasan, R.; Blake, R. A.; Song, A.; Staben, S. T.; Zhang, Y.; Arnott, D.; Fairbrother, W. J.; Foster, S. A.; Wertz, I. E.; Ciferri, C.; Dueber, E. C. Targeted Degradation via Direct 26S Proteasome Recruitment. Nature Chemical Biology, 2023, 19(1), 55–63. doi: 10.1038/s41589-022-01218-w
  4. de Paiva, I. M.; Vakili, M. R.; Soleimani, A. H.; Tabatabaei Dakhili, S. A.; Munira, S.; Paladino, M.; Martin, G.; Jirik, F. R.; Hall, D. G.; Weinfeld, M.; Lavasanifar, A. Biodistribution and Activity of EGFR Targeted Polymeric Micelles Delivering a New Inhibitor of DNA Repair to Orthotopic Colorectal Cancer Xenografts with Metastasis. Mol. Pharmaceutics, 2022, 19(6), 1825–1838. doi: 10.1021/acs.molpharmaceut.1c00918
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Cy® is a trademark of Cytiva.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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