Cyanine5.5 azide

Cat. # Quantity Price Lead time
14030 100 uL, 10 mM/DMSO –   in stock
34030 500 uL, 10 mM/DMSO $199 in stock
44030 1 mL, 10 mM/DMSO $495 in stock
A4030 1 mg –   in stock
B4030 5 mg $199 in stock
C4030 10 mg $297 in stock
D4030 25 mg $495 in stock
E4030 50 mg $895 in stock
F4030 100 mg $1490 in stock
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This Cyanine5.5 labeling reagent is a dye azide for click chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5® and DyLight 680.

Absorbance and emission spectra of Cyanine5.5

Absorbance and emission spectra of Cyanine5.5

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General properties

Appearance: dark blue powder / solution
Molecular weight: 701.34
Molecular formula: C43H49ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (1.6 uM, 1.2 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Kang, J.‐Y.; Mun, D.; Chun, Y.; Park, D.‐S.; Kim, H.; Yun, N.; Joung, B. Engineered small extracellular vesicle‑mediated NOX4 siRNA delivery for targeted therapy of cardiac hypertrophy. Journal of Extracellular Vesicles, 2023, 12(10), 12371. doi: 10.1002/jev2.12371
  2. Bashore, C.; Prakash, S.; Johnson, M. C.; Conrad, R. J.; Kekessie, I. A.; Scales, S. J.; Ishisoko, N.; Kleinheinz, T.; Liu, P. S.; Popovych, N.; Wecksler, A. T.; Zhou, L.; Tam, C.; Zilberleyb, I.; Srinivasan, R.; Blake, R. A.; Song, A.; Staben, S. T.; Zhang, Y.; Arnott, D.; Fairbrother, W. J.; Foster, S. A.; Wertz, I. E.; Ciferri, C.; Dueber, E. C. Targeted Degradation via Direct 26S Proteasome Recruitment. Nature Chemical Biology, 2023, 19(1), 55–63. doi: 10.1038/s41589-022-01218-w
  3. de Paiva, I. M.; Vakili, M. R.; Soleimani, A. H.; Tabatabaei Dakhili, S. A.; Munira, S.; Paladino, M.; Martin, G.; Jirik, F. R.; Hall, D. G.; Weinfeld, M.; Lavasanifar, A. Biodistribution and Activity of EGFR Targeted Polymeric Micelles Delivering a New Inhibitor of DNA Repair to Orthotopic Colorectal Cancer Xenografts with Metastasis. Mol. Pharmaceutics, 2022, 19(6), 1825–1838. doi: 10.1021/acs.molpharmaceut.1c00918
  4. Mekhail, K.; Lee, M.; Sugiyama, M.; Astori, A.; St-Germain, J.; Latreille, E.; Khosraviani, N.; Wei, K.; Li, Z.; Rini, J.; Lee, W. L.; Antonescu, C.; Raught, B.; Fairn, G. D. FASN Inhibitor TVB-3166 Prevents S-Acylation of the Spike Protein of Human Coronaviruses. Journal of Lipid Research, 2022, 63(9), 100256. doi: 10.1016/j.jlr.2022.100256
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