Cyanine5.5 azide

Cat. # Quantity Price Lead time
14030 100 uL, 10 mM/DMSO $110.00 5 days
34030 500 uL, 10 mM/DMSO $210.00 5 days
44030 1 mL, 10 mM/DMSO $410.00 in stock
A4030 1 mg $110.00 in stock
B4030 5 mg $210.00 in stock
C4030 10 mg $310.00 in stock
D4030 25 mg $410.00 in stock
E4030 50 mg $695.00 in stock

This Cyanine5.5 labeling reagent is a dye azide for Click Chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5®, Alexa Fluor 680, and DyLight 680.

Cy5.5 absorbance and emission spectra

Cy5.5 absorbance and emission spectra

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General properties

Appearance: dark blue powder / solution
Molecular weight: 701.34
Molecular formula: C43H49ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (1.6 uM, 1.2 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Al-Lawati, H.; Vakili, M.R.; Lavasanifar, A.; Ahmed, S.; Jamali, F. Reduced heart exposure of diclofenac by its polymeric micellar formulation, normalizes CYP- mediated metabolism of arachidonic acid imbalance in adjuvant arthritis rat model: Implications in reduced cardiovascular side effects of diclofenac by nano-drug d. Molecular Pharmaceutics, in press. doi: 10.1021/acs.molpharmaceut.0c00069
  2. Al-Lawati, H.; Vakili, M.R.; Lavasanifar, A.; Ahmed, S.; Jamali, F. Delivery and biodistribution of traceable polymeric micellar diclofenac in the rat. Journal of Pharmaceutical Sciences, 2019, 108(8), 2698–2707. doi: 10.1016/j.xphs.2019.03.016
  3. Sun, H.; Yan, L.; Chang, M.Y.Z.; Carter, K.; Zhang, R.; Slyker, L.; Lovell, J.; Wu, Y.; Cheng, C. A multifunctional biodegradable brush polymer-drug conjugate for paclitaxel/gemcitabine co-delivery and tumor imaging. Nanoscale Advances, 2019, 1(7), 2761–2771. doi: 10.1039/c9na00282k
  4. Carniato, F.; Alberti, D.; Lapadula, A.; Martinelli, J.; Isidoro, C.; Crich, S.G.; Tei, L. Multifunctional Gd-based mesoporous silica nanotheranostic for anticancer drug delivery. Journal of Materials Chemistry B, 2019, 7(19), 3143–3152. doi: 10.1039/c9tb00375d
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