Cyanine7 alkyne

Cat. # Quantity Price Lead time
A50B0 1 mg $110.00 in stock
B50B0 5 mg $210.00 in stock
C50B0 10 mg $310.00 in stock
D50B0 25 mg $410.00 in stock
E50B0 50 mg $695.00 in stock
F50B0 100 mg $1190.00 in stock

Alkyne derivative of Cyanine7, a near infrared fluorophore, analog of Cy7®. The alkyne can be conjugated to a variety of azides via copper-catalyzed Click chemistry.

The dye has limited solubility in water, but it can be successfully conjugated in aqueous buffers with the addition of DMSO or DMF.

Cyanine7 absorbance and emission spectra

Cyanine7 absorbance and emission spectra

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Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cyanine3 alkyne

A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.

Cyanine7.5 alkyne

Reactive near infrared (NIR) dye for Click Chemistry containing a terminal alkyne group.

General properties

Appearance: green powder
Mass spec M+ increment: 586.4
Molecular weight: 622.28
CAS number: 1998119-13-3 (chloride), 1954687-62-7
Molecular formula: C40H48ClN3O
Solubility: good in DMSO, DMF, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

Product citations

  1. Conibear, A.C.; Thewes, K.; Groysbeck, N.; Becker, C.F.W. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry, 2019, 7, 113. doi: 10.3389/fchem.2019.00113
  2. Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
  3. Smith, A.A.A.; Zuwala, K.; Pilgram, O.; Johansen, K.S.; Tolstrup, M.; Dagnæs-Hansen, F.; Zelikin, A.N. Albumin-Polymer-Drug Conjugates: Long Circulating, High Payload Drug Delivery Vehicles. ACS Macro Letters, 2016, 5, 1089–1094. doi: 10.1021/acsmacrolett.6b00544
  4. Zhang, L.; Thurber, G.M. Quantitative Impact of Plasma Clearance and Down-regulation on GLP-1 Receptor Molecular Imaging. Molecular Imaging and Biology, 2016, 18(1), 79–89. doi: 10.1007/s11307-015-0880-2
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