Biotin alkyne

Cat. # Quantity Price Lead time
C37B0 10 mg $90.00 in stock
D37B0 25 mg $160.00 in stock
E37B0 50 mg $270.00 in stock
F37B0 100 mg $420.00 in stock

Biotin alkyne for the preparation of various biotinylated conjugates via Click Chemistry.

This alkyne reacts with various azides, including biomolecules containing azide groups. Biotinylated conjugates can be used for various assays and applications requiring affinity binding.

Our recommended protocol can be used for the conjugation.

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Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

Coumarin 343 X azide

Coumarin 343 is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by Click chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility, and provides spatial separation between the dye and the biomolecule.

Sulfo-Cyanine3 carboxylic acid

Sulfo-Cyanine3 free unactivated monofunctional carboxylic acid, water-soluble dye.

General properties

Appearance: colorless solid
Molecular weight: 281.37
Molecular formula: C13H19N3O2S
Solubility: good in DMSO and DMF, low in water
Quality control: NMR 1H (95%), TLC, functional testing
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

Product citations

  1. Rink, W.M.; Thomas, F. Decoration of Coiled-Coil Peptides with N-Cysteine Peptide Thioesters As Cyclic Peptide Precursors Using Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) Click Reaction. Organic Letters, 2018, 20(23), 7493–7497. doi: 10.1021/acs.orglett.8b03261
  2. Cui, X.-Y.; Sun, N.-N.; Xie, X.-N.; Sun, W.-C.; Zhao, Q.; Liu, N. Detection of Newly Synthesized Proteins via Metabolic Incorporation of Non-natural Amino Acid. Chinese Journal of Analytical Chemistry, 2018, 46(11), 1808–1813. doi: 10.1016/s1872-2040(18)61125-9
  3. Ullrich, M.; Liang, V.; Chew, Y.L.; Banister, S.; Song, X.; Zaw, T.; Lam, H.; Berber, S.; Kassiou, M.; Nicholas, H.R. et al. Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans. Nature Protocols, 2014, 9(9), 2237-2255. doi: 10.1038/nprot.2014.150
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