Cyanine7.5 amine

Cat. # Quantity Price Lead time
160C0 1 mg $110.00 in stock
260C0 5 mg $210.00 in stock
360C0 10 mg $310.00 in stock
460C0 25 mg $410.00 in stock
560C0 50 mg $695.00 5 days
660C0 100 mg $1190.00 in stock

Cyanine7.5 is a NIR fluorescent dye. This reagent contains free amino group which can be used coupled with activated carboxylic acid derivatives.

Cy7.5 absorbance and emission spectra

Cy7.5 absorbance and emission spectra

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Sulfo-Cyanine7.5 NHS ester

A water soluble near infrared emitting dye for in vivo imaging applications. Sulfo-Cyanine7.5 is an analog of indocyanine green (ICG) possessing higher emission quantum yield, and containing a linker arm.

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 is a near infrared fluorophore similar to indocyanine green (ICG), but possessing higher fluorescence quantum yield. The dye is very hydrophilic and water soluble. The reagent is very useful for the labeling of biomolecules for in vivo imaging. This is an alkyne for copper catalyzed Click chemistry.

General properties

Appearance: dark green powder
Molecular weight: 819.99
CAS number: 2104005-17-4 (hydrichloride), 2104005-16-3 (chloride), 2104005-15-2
Molecular formula: C51H64Cl2N4O
Solubility: good in DMSO, DMF, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

Product citations

  1. Yang, X.; Wang, Z.; Huang, H.; Ling, S.; Zhang, R.; Zhang, Y.; Chen, G.; Li, C.; Wang, Q. A Targeted Activatable NIR-IIb Nanoprobe for Highly Sensitive Detection of Ischemic Stroke in a Photothrombotic Stroke Model. Advanced Healthcare Materials, 2021, 10(5), 2001544. doi: 10.1002/adhm.202001544
  2. Bhattacharya, D.S.; Svechkarev, D.A.; Bapat, A.; Patil, P.; Hollingsworth, M.A.; Mohs, A.M. Sulfation modulates the targeting properties of hyaluronic acid to P-selectin and CD44. ACS Biomaterials Science & Engineering, 2020, 6(6), 3585–3598. doi: 10.1021/acsbiomaterials.0c00115
  3. Qi, B.; Crawford, A.J.; Wojtynek, N.E.; Talmon, G.A.; Hollingsworth, M.A.; Ly, Q.P.; Mohs, A.M. Tuned near infrared fluorescent hyaluronic acid conjugates for delivery to pancreatic cancer for intraoperative imaging. Theranostics, 2020, 10(8), 3413–3429. doi: 10.7150/thno.40688
  4. Retout, M.; Brunetti, E.; Valkenier, H.; Bruylants, G. Limits of thiol chemistry revealed by quantitative analysis of mixed layers of thiolated-PEG ligands grafted onto gold nanoparticles. Journal of Colloid and Interface Science, 2019, 557, 807–815. doi: 10.1016/j.jcis.2019.09.047
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