Sulfo-Cyanine3 tetrazine

sulfo-Cyanine3 Tetrazine Copper-free click chemistry
Cat. # Quantity Price Lead time
113E0 1 mg $110.00 in stock
213E0 5 mg $290.00 in stock
313E0 10 mg $460.00 in stock
413E0 25 mg $690.00 in stock
513E0 50 mg $1270.00 in stock
613E0 100 mg $1990.00 in stock
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Tetrazine - trans-cyclooctene ligation is among the fastest bioconjugation reactions known to date.

This water soluble sulfo-Cyanine3 derivative contains methyltetrazine moiety for the coupling with trans-cyclooctenes. Methyltetrazines possess optimal stability at physiological pH, while maintaining extremely high reactivity towards cyclooctenes.

The fluorophore is bright, photostable, and is also very well visible with naked eye.

Sulfo-Cyanine3 tetrazine, 613E0
Sulfo-Cyanine3 tetrazine, 613E0
Sulfo-Cyanine3 tetrazine, 613E0
Structure of sulfo-Cy3 tetrazine
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Sulfo-Cyanine7 tetrazine

Near infrared, water soluble dye methyltetrazine for the conjugation with strained cycloalkenes in TCO ligation reaction.

General properties

Appearance: red powder
Molecular weight: 838.05
Molecular formula: C40H44KN7O7S2
IUPAC name: Potassium (E)-2-[(E)-3-{3,3-Dimethyl-1-[6-({[p-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl}amino)-6-oxohexyl]-5-(oxysulfonyl)-3H-indol-2-yl}-2-propenylidene]-1-methyl-3,3-dimethyl-5-indolinesulfonate
Solubility: soluble in water (0.43 M = 36 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06
Cy® is a trademark of GE Healthcare.
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