Sulfo-Cyanine3 tetrazine

Cat. # Quantity Price Lead time
113E0 1 mg $110.00 in stock
213E0 5 mg $290.00 in stock
313E0 10 mg $460.00 in stock
413E0 25 mg $690.00 in stock
513E0 50 mg $1270.00 in stock
613E0 100 mg $1990.00 in stock

Tetrazine - trans-cyclooctene ligation is among the fastest bioconjugation reactions known to date.

This water soluble sulfo-Cyanine3 derivative contains methyltetrazine moiety for the coupling with trans-cyclooctenes. Methyltetrazines possess optimal stability at physiological pH, while maintaining extremely high reactivity towards cyclooctenes.

The fluorophore is bright, photostable, and is also very well visible with naked eye.

Absorption and emission spectra of sulfo-Cyanine3 fluorophore

Absorption and emission spectra of sulfo-Cyanine3 fluorophore

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General properties

Appearance: red powder
Molecular weight: 838.05
Molecular formula: C40H44KN7O7S2
IUPAC name: Potassium (E)-2-[(E)-3-{3,3-Dimethyl-1-[6-({[p-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl}amino)-6-oxohexyl]-5-(oxysulfonyl)-3H-indol-2-yl}-2-propenylidene]-1-methyl-3,3-dimethyl-5-indolinesulfonate
Solubility: soluble in water (0.43 M = 36 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06
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