sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 Cycloalkynes Copper-free click chemistry

Cat. #	Quantity	Price	Lead time
173F0	1 mg	$125	in stock
273F0	5 mg	$325	in stock
473F0	25 mg	$850	in stock
573F0	50 mg	$1490	in stock
673F0	100 mg	$1990	in stock

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Sulfo-Cyanine5.5 is a dye with far-red emission approaching the NIR range. It has found application in non-invasive live-organism imaging. This particular derivative of sulfo-Cyanine5.5, the DBCO (or ADIBO) derivative, contains cycloalkyne for copper-free conjugation of this fluorophore with various organic azides.

The reaction between DBCO and azides is blazingly fast, orders of magnitude exceeding the rate of copper-catalyzed reaction between azides and terminal alkynes. It is also catalyst-free.

This reagent can be used to conjugate sulfo-Cyanine5.5 dye to a variety of azide-labeled molecules.

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Absorption and emission spectra of sulfo-Cyanine5.5

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Cyanine5.5 alkyne is a NIR (near infrared) dye azide for copper-catalyzed сlick сhemistry.

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Copper(II)-TBTA complex

A catalyst for click reaction. A stable copper(II) complex which must be converted to monovalent copper(I) in situ using reducing agents. The complex can be used to prepare a reaction buffer of any composition.

sulfo-Cyanine3 DBCO

sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water-soluble fluorophore sulfo-Cyanine3 for copper-free click chemistry.

General properties

Appearance:	dark blue solid
Molecular weight:	1317.69
Molecular formula:	C₆₁H₅₉N₄K₃O₁₄S₄
Solubility:	good in water, DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	673
ε, L⋅mol⁻¹⋅cm⁻¹:	211000
Emission maximum, nm:	691
Fluorescence quantum yield:	0.21

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.