Sulfo-Cyanine5 NHS ester

Cat. # Quantity Price Lead time
13320 1 mg $110.00 in stock
23320 5 mg $210.00 in stock
43320 25 mg $410.00 in stock
53320 50 mg $695.00 in stock
63320 100 mg $1190.00 in stock

Water soluble Cyanine 5 succinimidyl ester (SE), an equivalent of Cy5® NHS ester, for the labeling of various amine-containing molecules in aqueous phase without use of any organic co-solvent. This product is therefore particularly useful for the labeling of proteins which denature in the presence of organic co-solvents, as well as for proteins with low solubility.

Sulfo-Cyanine 5 is an analog of Cy5®, one of the most popular fluorophores which is compatible with various equipment such as plate readers, microscopes, and imagers.

This dye is highly hydrophilic and water-soluble. A non-sulfonated analog is also available.

Can be used as a replacement for Cy5®, Alexa Fluor 647, DyLight 649 for all applications.

Sulfo-Cyanine 5 absorbance and emission spectra

Sulfo-Cyanine 5 absorbance and emission spectra

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Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Cyanine7 carboxylic acid

Non-reactive, near-infrared fluorescent dye.

General properties

Appearance: dark blue powder
Molecular weight: 777.95
CAS number: 2230212-27-6 (potassium salt); 937739-58-7 (inner salt)
Molecular formula: C36H40N3KO10S2
Solubility: very good in water, good in DMF and DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Product citations

  1. Shukla, Sourabh and Roe, Anne Jessica and Liu, Ruifu and Veliz, Frank A. and Commandeur, Ulrich and Wald, David N. and Steinmetz, Nicole F. Affinity of plant viral nanoparticle potato virus X (PVX) towards malignant B cells enables cancer drug delivery. Biomaterials Science, in press. doi: 10.1039/D0BM00683A
  2. Mohammad-Beigi, H.; Hayashi, Y.; Zeuthen, C.M.; Eskandari, H.; Scavenius, C.; Juul-Madsen, K.; Vorup-Jensen, T.; Enghild, J.J.; Sutherland, D.S. Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association. bioRxiv, preprint. doi: 10.1101/2020.02.05.924480
  3. Sheshachala, S.; Grösche, M.; Scherr, T.; Hu, Y.; Sun, P.; Bartschat, A.; Mikut, R; Niemeyer, C.M. Segregation of dispersed silica nanoparticles in microfluidic water in oil droplets: A kinetic study. ChemPhysChem, 2020, 21(10), 1070–1078. doi: 10.1002/cphc.201901151
  4. Sabeti Azad, M.; Okuda, M.; Cyrenne, M.; Bourge, M.; Heck, M.-P.; Yoshizawa, S.; Fourmy, D. Fluorescent Aminoglycoside Antibiotics and Methods for Accurately Monitoring Uptake by Bacteria. ACS Infectious Diseases, 2020, 6(5), 1008–1017. doi: 10.1021/acsinfecdis.9b00421
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