Cyanine3 hydrazide

Hydrazides Cyanine3

Cat. #	Quantity	Price	Lead time
11070	1 mg	$125	in stock
21070	5 mg	$260	in stock
41070	25 mg	$510	in stock
51070	50 mg	$895	in stock
61070	100 mg	$1490	in stock

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Cyanine3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide.

This reagent allows to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone oxidative stress or deamination, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.

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Cyanine3 absorbance and emission spectra

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General properties

Appearance:	red powder
Molecular weight:	543.57
Molecular formula:	C₃₀H₄₀Cl₂N₄O
Solubility:	moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control:	NMR ¹H and HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	555
ε, L⋅mol⁻¹⋅cm⁻¹:	150000
Emission maximum, nm:	570
Fluorescence quantum yield:	0.31
CF₂₆₀:	0.04
CF₂₈₀:	0.09

Product citations

Shang, Z.; Zhang, S.; Wang, J.; Zhou, L.; Zhang, X.; Billadeau, D.D.; Yang, P.; Zhang, L.; Zhou, F.; Bai, P.; Jia, D. TRIM25 predominately associates with anti-viral stress granules. Nature Communications, 2024, 15, 4127. doi: 10.1038/s41467-024-48596-4
Wang, Y.; Ling, X.; Zhang, C.; Zou, J.; Luo, B.; Luo, Y.; Jia, X.; Jia, G.; Zhang, M.; Hu, J.; Liu, T.; Wang, Y.; Lu, K.; Li, D.; Ma, J.; Liu, C.; Su, Z. Modular Characterization of SARS-CoV-2 Nucleocapsid Protein Domain Functions in Nucleocapsid-like Assembly. Molecular Biomedicine, 2023, 4(1), 16. doi: 10.1186/s43556-023-00129-z
Zhao, Meng and Börner, Richard and Sigel, Roland K. O. and Freisinger, Eva. Site-Specific Dual-Color Labeling of Long RNAs. Methods in Molecular Biology, 2020, 2106, 253–270. doi: 10.1007/978-1-0716-0231-7_16
Zhang, J.; Chetnani, B.; Cormack, E.D.; Alonso, D.; Liu, W.; Mondragon, A.; Fei, J. Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand. eLife, 2018, 7, e39518. doi: 10.7554/eLife.39518

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Cy® is a trademark of GE Healthcare.

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.