Copper(II)-TBTA complex

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21050 1.5 mL $75 in stock
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A component of our recommended catalyst for conjugating azides with alkynes using a copper-catalyzed click reaction. This inactive complex is stable and contains divalent copper(II) as 10 mM CuSO4 in 55% aqueous DMSO.

When Cu(II)-TBTA is treated with reducing agents, such as ascorbic acid, a catalytically active complex with monovalent copper (I) is formed.

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General properties

Appearance: blue solution
Molecular weight: 690.23
Molecular formula: C30H30CuN10O4S
Quality control: functional testing (click chemistry)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

Product citations

  1. Haugen, R.J.; Barnier, C.; Elrod, N.D.; Luo, H.; Jensen, M.K.; Ji, P.; Smibert, C.A.; Lipshitz, H.D.; Wagner, E.J.; Lydia Freddolino, P.; Goldstrohm, A.C. Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase. bioRxiv, 2023. doi: 10.1101/2023.08.29.555372
  2. Kropacheva, N. O.; Golyshkin, A. A.; Vorobyeva, M. A.; Meschaninova, M. I. Convenient Solid-Phase Attachment of Small-Molecule Ligands to Oligonucleotides via a Biodegradable Acid-Labile P-N-Bond. Molecules, 2023, 28(4), 1904. doi: 10.3390/molecules28041904
  3. Novopashina, D. S.; Dymova, M. A.; Davydova, A. S.; Meschaninova, M. I.; Malysheva, D. O.; Kuligina, E. V.; Richter, V. A.; Kolesnikov, I. A.; Taskaev, S. Y.; Vorobyeva, M. A. Aptamers for Addressed Boron Delivery in BNCT: Effect of Boron Cluster Attachment Site on Functional Activity. International Journal of Molecular Sciences, 2023, 24(1), 306. doi: 10.3390/ijms24010306
  4. De Prisco, N.; Ford, C.; Elrod, N. D.; Lee, W.; Tang, L. C.; Huang, K.-L.; Lin, A.; Ji, P.; Jonnakuti, V. S.; Boyle, L.; Cabaj, M.; Botta, S.; Õunap, K.; Reinson, K.; Wojcik, M. H.; Rosenfeld, J. A.; Bi, W.; Tveten, K.; Prescott, T.; Gerstner, T.; Schroeder, A.; Fong, C.-T.; George-Abraham, J. K.; Buchanan, C. A.; Hanson-Khan, A.; Bernstein, J. A.; Nella, A. A.; Chung, W. K.; Brandt, V.; Jovanovic, M.; Targoff, K. L.; Yalamanchili, H. K.; Wagner, E. J.; Gennarino, V. A. Alternative Polyadenylation Alters Protein Dosage by Switching between Intronic and 3′UTR Sites. Sci. Adv., 2023, 9(7), eade4814. doi: 10.1126/sciadv.ade4814
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