BDP® 650/665-X-NHS ester

NHS esters BDP® 650/665 Near infrared (NIR) imaging

Cat. #	Quantity	Price	Lead time
1E420	1 mg	$125	in stock
2E420	5 mg	$260	in stock
4E420	25 mg	$510	in stock
5E420	50 mg	$895	in stock
6E420	100 mg	$1490	in stock

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BDP^® 650/665 is a borondipyrromethene dye with far-red excitation and emission. The dye has a good molar extinction coefficient and emission quantum yield.

The NHS ester can be conjugated with amine groups of proteins, peptides, and other molecules. The molecule contains an additional aminohexanoic acid linker.

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Absorption and emission spectra of BDP 650/665

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THPTA ligand

THPTA is a water-soluble ligand for Cu(I)-catalyzed click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

General properties

Appearance:	dark colored solid
Mass spec M+ increment:	528.2
Molecular weight:	643.45
CAS number:	235439-04-0; 1616842-78-4
Molecular formula:	C₃₃H₃₂N₅BF₂O₆
Solubility:	good in DMF, DMSO, low in water
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	649
ε, L⋅mol⁻¹⋅cm⁻¹:	94000
Emission maximum, nm:	667
Fluorescence quantum yield:	0.52
CF₂₆₀:	0.04
CF₂₈₀:	0.04

Product citations

Roussel, S.; Grenier, P.; Chénard, V.; Bertrand, N. Dual-Labelled Nanoparticles Inform on the Stability of Fluorescent Labels In Vivo. Pharmaceutics 2023, 15 (3), 769., 2023, 15(3), 769. doi: 10.3390/pharmaceutics15030769
Daumar, P.; Goisnard, A.; Dubois, C.; Roux, M.; Depresle, M.; Penault-Llorca, F.; Bamdad, M.; Mounetou, E. Chemical biology fluorescent tools for in vitro investigation of the multidrug resistant P-glycoprotein (P-gp) expression in tumor cells. RSC Advances, 2023, 13(39), 27016-27035. doi: 10.1039/d3ra05093a

BDP^® is a trademark of Lumiprobe

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.