TAMRA azide, 5-isomer

TAMRA (TMR, Tetramethylrhodamine) Azides Click chemistry
Cat. # Quantity Price Lead time
A7130 1 mg $110 in stock
B7130 5 mg $135 in stock
C7130 10 mg $210 in stock
D7130 25 mg $390 5 days
E7130 50 mg $595 in stock
F7130 100 mg $790 in stock
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TAMRA (TMR, tetramethylrhodamine) azide, solid compound, and 10 mM solution in DMSO, labeling reagent for click chemistry. Pure 5-isomer. TAMRA is often used as a FRET acceptor for FAM fluorophore. Can replace DyLight 549.

TAMRA azide, 5-isomer, F7130
TAMRA azide, 5-isomer, F7130
TAMRA azide, 5-isomer, F7130
5-TAMRA azide structure
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Absorption and emission spectra of 5-TAMRA

Absorption and emission spectra of 5-TAMRA

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General properties

Appearance: violet solid / solution
Mass spec M+ increment: 512.2
Molecular weight: 512.56
CAS number: 825651-66-9
Molecular formula: C28H28N6O4
Solubility: good in polar organic solvents (DMF, DMSO, alcohols), low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

Product citations

  1. Yu, T.; Hou, D.; Zhao, J.; Lu, X.; Greentree, W.K.; Zhao, Q.; Yang, M.; Conde, D.-G.; Linder, M.E.; Lin, H. NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation. Cell reports, 2024, 43(4), 114070. doi: 10.1016/j.celrep.2024.114070
  2. Liu, Y.; Hou, D.; Chen, W.; Lu, X.; Komaniecki, G.P.; Xu, Y.; Yu, T.; Zhang, S.M.; Linder, M.E.; Lin, H. MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(34), e2403392121. doi: 10.1073/pnas.2403392121
  3. Komaniecki, G.; Camarena, M. D. C.; Gelsleichter, E.; Mendoza, R.; Subler, M.; Windle, J. J.; Dozmorov, M. G.; Lai, Z.; Sarkar, D.; Lin, H. Astrocyte Elevated Gene-1 Cys75 S-Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry, 2023, 62(2), 543–553. doi: 10.1021/acs.biochem.2c00583
  4. Reddi, R. N.; Rogel, A.; Gabizon, R.; Rawale, D. G.; Harish, B.; Marom, S.; Tivon, B.; Arbel, Y. S.; Gurwicz, N.; Oren, R.; David, K.; Liu, J.; Duberstein, S.; Itkin, M.; Malitsky, S.; Barr, H.; Katz, B.-Z.; Herishanu, Y.; Shachar, I.; Shulman, Z.; London, N. Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry. J. Am. Chem. Soc, 2023, 145(6), 3346–3360. doi: 10.1021/jacs.2c08853
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Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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