TAMRA azide, 5-isomer

Cat. # Quantity Price Lead time
17130 100 uL, 10 mM/DMSO $110.00 in stock
37130 500 uL, 10 mM/DMSO $210.00 in stock
47130 1 mL, 10 mM/DMSO $410.00 in stock
A7130 1 mg $110.00 in stock
B7130 5 mg $210.00 in stock
C7130 10 mg $310.00 in stock
D7130 25 mg $410.00 in stock
E7130 50 mg $695.00 in stock
F7130 100 mg $1190.00 in stock
Delivery options for stock items

TAMRA (TMR, tetramethylrhodamine) azide, solid compound, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. Pure 5-isomer.

TAMRA is often used as FRET acceptor for FAM fluorophore.

Can replace Alexa Fluor 555, DyLight 549.

Absorption and emission spectra of 5-TAMRA

Absorption and emission spectra of 5-TAMRA

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General properties

Appearance: violet solid / solution
Mass spec M+ increment: 512.2
Molecular weight: 512.56
CAS number: 825651-66-9
Molecular formula: C28H28N6O4
Solubility: good in polar organic solvents (DMF, DMSO, alcohols), low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download

Spectral properties

Excitation maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

Product citations

  1. Li, W.; Zhou, Y.; Tang, G.; Wong, N.-K.; Yang, M.; Tan, D.; Xiao, Y. Chemoproteomics Reveals the Anti-proliferative Potential of Parkinson's Disease Kinase Inhibitor LRRK2-IN-1 by Targeting PCNA Protein. Molecular Pharmaceutics, in press. doi: 10.1021/acs.molpharmaceut.8b00325
  2. Moynihan, K.D.; Holden, R.L.; Mehta, N.K.; Wang, C.; Karver, M.R.; Dinter, J.; Liang, S.; Abraham, W.; Melo, M.B.; Zhang, A.Q.; Li, N.; Le Gall, S.; Pentelute, B.; Irvine, D.J. Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability. Cancer Immunology Research, in press. doi: 10.1158/2326-6066.CIR-17-0607
  3. Spangler, B.; Dovala, D.; Sawyer, W.S.; Thompson, K.V.; Six, D.A.; Reck, F.; Feng, B.Y. Molecular probes for the determination of sub-cellular compound exposure profiles in Gram-negative bacteria. ACS Infectious Diseases, in press. doi: 10.1021/acsinfecdis.8b00093
  4. Nemmara, V.J.; Subramanian, V.; Muth, A.; Mondal, S.; Salinger, A.J.; Maurais, A.J.; Tilvawala, R.; Weerapana, E.; Thompson, P.R. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). ACS Chemical Biology, 2018, 13(3), 712–722. doi: 10.1021/acschembio.7b00957
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