Cyanine7 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 15020 | 1 mg | $125.00 | in stock | |
| 25020 | 5 mg | $260.00 | in stock | |
| 45020 | 25 mg |
$510.00
|
in stock | |
| 55020 | 50 mg |
$895.00
|
in stock | |
| 65020 | 100 mg |
$1490.00
|
in stock |
Amine reactive Cyanine7, near infrared fluorescent dye, an improved analog of Cy7®.
NIR fluorophores can be used to take advantage of near infrared window of biological tissues - increased transparency of tissues in this spectral region allows to carry out in vivo imaging.
This reagent can be utilized to produce Cyanine7-labeled biomolecules for subsequent use in various in vivo research, and drug design related experiments.
The structure of Cyanine7 features rigidized design of central polymethyne chain. This molecular reinforcement allows to increase quantum yield by 20% compared with parent structure, increasing fluorescence brightness.
This reagent requires organic co-solvent for the labeling (please see Recommended Protocols section below). Water-soluble Cyanine7 NHS ester is also available, and recommended for protein NIR labeling.
Cy7 absorbance and emission spectra
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General properties
| Appearance: | dark green solid |
| Molecular weight: | 733.64 |
| CAS number: | 2408482-09-5 |
| Molecular formula: | C41H48N3BF4O4 |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 199000 |
| Emission maximum, nm: | 773 |
| Fluorescence quantum yield: | 0.3 |
| CF260: | 0.022 |
| CF280: | 0.029 |
Product citations
- Ehrman, R. N.; Brohlin, O. R.; Wijesundara, Y. H.; Kumari, S.; Trashi, I.; Trashi, O.; Howlett, T. S.; Herbert, F. C.; Raja, A.; Koirala, S.; Tran, N.; Al-Kharji, N. M.; Hagge, L. M.; Gassensmith, J. A Scalable Synthesis of Adjuvanting Antigen Depots Based on Met-al-Organic Frameworks. ChemRxiv, 2023, preprint. doi: 10.26434/chemrxiv-2023-gtl30
- Shushunova, N. A.; Mayorova, O. A.; Prikhozhdenko, E. S.; Goryacheva, O. A.; Kulikov, O. A.; Plastun, V. O.; Gusliakova, O. I.; Muslimov, A. R.; Inozemtseva, O. A.; Pyataev, N. A.; Shirokov, A. A.; Gorin, D. A.; Sukhorukov, G. B.; Sindeeva, O. A. Targeted Therapy for Glomerulonephritis Using Arterial Delivery of Encapsulated Etanercept. International Journal of Molecular Sciences, 2023, 24(3), 2784. doi: 10.3390/ijms24032784
- Wlodarczyk, M. T.; Dragulska, S. A.; Chen, Y.; Poursharifi, M.; Acosta Santiago, M.; Martignetti, J. A.; Mieszawska, A. J. Pt(II)-PLGA Hybrid in a PH-Responsive Nanoparticle System Targeting Ovarian Cancer. Pharmaceutics, 2023, 15(2), 607. doi: 10.3390/pharmaceutics15020607
- Rybkin, I.; Pinyaev, S.; Sindeeva, O.; German, S. V.; Koblar, M.; Pyataev, N.; Čeh, M.; Gorin, D.; Sukhorukov, G.; Lapanje, A. Modification of Bacterial Cells for in Vivo Remotely Guided Systems. Frontiers in Bioengineering and Biotechnology, 2023, 10, 1070851. doi: 10.3389/fbioe.2022.1070851
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