Cyanine7 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 15020 | 1 mg |
$169.50
|
in stock | |
| 25020 | 5 mg |
$339.90
|
in stock | |
| 45020 | 25 mg |
$559.90
|
in stock | |
| 55020 | 50 mg |
$999.00
|
in stock | |
| 65020 | 100 mg |
$1999.00
|
in stock |
Amine reactive Cyanine7, near infrared fluorescent dye, an improved analog of Cy7®.
NIR fluorophores can be used to take advantage of near infrared window of biological tissues - increased transparency of tissues in this spectral region allows to carry out in vivo imaging.
This reagent can be utilized to produce Cyanine7-labeled biomolecules for subsequent use in various in vivo research, and drug design related experiments.
The structure of Cyanine7 features rigidized design of central polymethyne chain. This molecular reinforcement allows to increase quantum yield by 20% compared with parent structure, increasing fluorescence brightness.
This reagent requires organic co-solvent for the labeling (please see Recommended Protocols section below). Water-soluble Cyanine7 NHS ester is also available, and recommended for protein NIR labeling.
Cy7 absorbance and emission spectra
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General properties
| Appearance: | dark green solid |
| Molecular weight: | 733.64 |
| CAS number: | 2408482-09-5 |
| Molecular formula: | C41H48N3BF4O4 |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 199000 |
| Emission maximum, nm: | 773 |
| Fluorescence quantum yield: | 0.3 |
| CF260: | 0.022 |
| CF280: | 0.029 |
Product citations
- Xiang, L.; Henderson, M. I.; Drennan, S.; Sabuncu, S.; Fischer, J. M.; Yildirim, A. Peptide Amphiphile–Nanoparticle Assemblies for Mechano-Chemo Combination Therapy. Nano Lett, 2025, 25(19), 7875–7884. doi: 10.1021/acs.nanolett.5c01112
- Mayorova, O. A.; Saveleva, M. S.; Terentyeva, D. A.; Gusliakova, O. I.; Sindeeva, O. A. Protocol of Whey Protein Isolate–Based Microgel Targeted Delivery in Mouse Kidney. Bio Protoc, 2025, 15(12), e5347. doi: 10.21769/BioProtoc.5347
- Xiao, Y.; Tong, Z.; Xu, H.; Jia, Z.; Wang, C.; Cao, Y.; Song, L.; Hao, S.; Yang, J.; Zhou, Y.; Xie, Y.; Wu, P.; He, T.; Wu, Y.; Petersen, R. B.; Peng, A.; Zhang, C.; Chen, H.; Zheng, L.; Huang, K. A Rationally Designed Injury Kidney Targeting Peptide Library and Its Application in Rescuing Acute Kidney Injury. Sci. Adv., 2025, 11(18), eadt3943. doi: 10.1126/sciadv.adt3943
- Seo, H.S.; Han, J.-H.; Lim, J.; Bae, G.-H.; Byun, M.J.; Wang, C.-P.J.; Han, J.; Park, J.; Park, H.H.; Shin, M.; Park, T.-E.; Kim, T.-H.; Kim, S.-N.; Park, W.; Park, C.G. Enhanced Post-Surgical Cancer Treatment Using Methacrylated Glycol Chitosan Hydrogel for Sustained DNA/Doxorubicin Delivery and Immunotherapy. Biomaterials Research, 2024, 28, 0008. doi: 10.34133/bmr.0008
Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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