TFA-Amino modifier CPG 500

Cat. # Quantity Price Lead time
11860 100 mg $60.00 in stock
21860 250 mg $120.00 in stock
31860 500 mg $230.00 in stock
41860 1 g $380.00 in stock
51860 5 g $1450.00 10 days

This high load, 500 Å controlled pore glass solid support is designed for the synthesis of oligonucleotides containing up to 50 bases with a 3'-amino group. Amino group is protected with trifluoroacetyl (TFA) protection which is easily removed under standard deblock conditions.

The reagent is based on hydroxyprolinol core - a universal non-nucleoside structure that is naturally 100% chiral (no isomers formed upon condensation), and stable to all conditions of oligonucleotide synthesis and deblock.

Customers also purchased with this product

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Long trebler phosphoramidite

Long trebler phosphoramidite is a branching reagent for DNA synthesis, allowing to prepare branched oligonucleotides, and dendrimers.
Add this product to your cart and
get free express delivery

Alkyne Phosphoramidite, 5'-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.

General properties

Appearance: off-white beads
Quality control: NMR 1H and HPLC-MS (95%) of bound reagent, loading measurement
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 70−90
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases

Product citations

  1. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.