TFA-Amino modifier CPG 500
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
11860 | 100 mg | $60.00 | in stock | |
21860 | 250 mg | $120.00 | in stock | |
31860 | 500 mg | $230.00 | in stock | |
41860 | 1 g | $380.00 | in stock | |
51860 | 5 g |
$1450.00
|
10 days | |
61860 | 10 g |
$2465.00
|
10 days |
This high load, 500 Å controlled pore glass solid support is designed for the synthesis of oligonucleotides containing up to 50 bases with a 3'-amino group. Amino group is protected with trifluoroacetyl (TFA) protection which is easily removed under standard deblock conditions.
The reagent is based on hydroxyprolinol core - a universal non-nucleoside structure that is naturally 100% chiral (no isomers formed upon condensation), and stable to all conditions of oligonucleotide synthesis and deblock.
Customers also purchased with this product
Alkyne CPG modifier 500
Solid support for the synthesis of 3'-modified oligonucleotides with alkyne group for Click Chemistry.get free express delivery
Cyanine5.5 NHS ester
Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.get free express delivery
Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO
Catalyst for bioconjugate synthesis by Click Chemistry.General properties
Appearance: | off-white beads |
Quality control: | NMR 1H and HPLC-MS (95%) of bound reagent, loading measurement |
Storage conditions: | Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate. |
MSDS: | Download |
Product specifications |
Oligo synthesis details
Pore size, Å: | 500 |
Typical loading, umol/g: | 50−80 |
Coupling conditions: | standard coupling, identical to normal nucleobases |
Cleavage conditions: | ammonia, 2 h at room temperature |
Deprotection conditions: | identical to protected nucleobases |
Product citations
- Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
