TFA-Amino modifier CPG 500

Oligonucleotide synthesis CPG (controlled pore glass) solid supports for oligonucleotide synthesis
Cat. # Quantity Price Lead time
11860 100 mg $60.00 in stock
21860 250 mg $120.00 in stock
31860 500 mg $230.00 in stock
41860 1 g $380.00 in stock
51860 5 g $1450.00 21 days
Bulk inquiry

This high load, 500 Å controlled pore glass solid support is designed for the synthesis of oligonucleotides containing up to 50 bases with a 3'-amino group. Amino group is protected with trifluoroacetyl (TFA) protection which is easily removed under standard deblock conditions.

The reagent is based on hydroxyprolinol core - a universal non-nucleoside structure that is naturally 100% chiral (no isomers formed upon condensation), and stable to all conditions of oligonucleotide synthesis and deblock.

TFA-Amino modifier CPG 500, 41860
TFA-Amino modifier CPG 500, 41860
TFA-Amino modifier CPG 500, 41860
TFA-Amino modifier CPG 500
Download in
ChemDraw format

Customers also purchased with this product

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.
Add this product to your cart and
get free express delivery

Alkyne CPG modifier 500

Solid support for the synthesis of 3'-modified oligonucleotides with alkyne group for Click Chemistry.
Add this product to your cart and
get free express delivery

Alkyne Amidite, hydroxyprolinol

Acetylenic amidite for the incorporation of acetylene groups into oligos.

General properties

Appearance: off-white beads
Quality control: NMR 1H and HPLC-MS (95%) of bound reagent, loading measurement
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 70−90
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases

Product citations

  1. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.