Alkyne CPG modifier 500
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 12860 | 100 mg | $60.00 | in stock | |
| 22860 | 250 mg | $120.00 | in stock | |
| 32860 | 500 mg | $230.00 | in stock | |
| 42860 | 1 g | $380.00 | in stock | |
| 52860 | 5 g |
$1450.00
|
in stock |
High loading controlled pore glass solid support for the synthesis of oligonucleotides with 3'-alkyne group. With this solid support, synthesis of oligos of up to 50 bases is possible.
Terminal alkyne group can be modified by copper catalyzed Click chemistry (see our recommended protocol for oligonucleotide modification).
This solid support is compatible with standard oligonucleotide deblocking conditions. No special deblocking is required.
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Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.General properties
| Appearance: | off-white beads |
| Quality control: | NMR 1H and HPLC (95%) of bound reagent, loading measurement |
| Storage conditions: | Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Oligo synthesis details
| Pore size, Å: | 500 |
| Typical loading, umol/g: | 70−90 |
| Coupling conditions: | standard coupling, identical to normal nucleobases |
| Cleavage conditions: | ammonia, 2 h at room temperature |
| Deprotection conditions: | identical to protected nucleobases |
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