Universal CPG type II, 500A

Cat. # Quantity Price Lead time
3219-1g 1 g $45.00 in stock
3219-10g 10 g $410.00 10 days

The Universal CPG type II, 500A is used for oligonucleotides synthesis to increase rate of dephosphorylation of the 3' end oligonucleotide during deblocking due to a rigid bicyclic molecule on the support.

The Universal CPG type II, 500A is suitable for use in harsh conditions and makes cleavage and deprotection with anhydrous ammonia gas-phase, ammonium hydroxide/methylamine (AMA) mixture or other basic reagents faster compared to universal Controlled Pore Glass (CPG) supports. Pore size of 500 Å is recommended for the synthesis of oligonucleotides up to 120 bases. For oligos up to 120 bases universal support 1000 Å can be used.

Usage

Coupling: Standard conditions for universal CPG.

Deprotection: 2 hours at 80°C or 8 hours at 55°C using concentrated ammonia; 15 minutes at 65°C using AMA mixture, ammonium hydroxide - 40% methylamine (1:1).

Customers also purchased with this product

Universal CPG type I, 500A

This universal support is intended for automated synthesis of oligonucleotides without the 3’ terminus modifications under harsh deblock conditions and extended cleavage times. Pore size of 500 Å is recommended for the synthesis of oligonucleotides up to 50 bases in length.

DusQ2 CPG 1000

Controlled pore glass (CPG) 1000 modified support for the synthesis of oligonucleotides with DusQ2 quencher at the 3’ end. Compatible with standard deblocking conditions.
Add this product to your cart and
get free express delivery

Cyanine5 phosphoramidite

Phosphoramidite derivative of Cyanine5 for the use in oligonucleotide synthesis.
Add this product to your cart and
get free express delivery
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.