DND-167, blue fluorescent pH indicator

Cat. # Quantity Price Lead time
/ 1 mM solution
20 x 50 uL
$380 1 days
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DND-167 (known as LysoSensor™ Blue DND-167, LysoView Blue) is a cell-permeable weak base that selectively accumulates in acidic vesicles after being protonated. The dye has a higher quantum yield in acidic environments with pKa at ~5.1, allowing visualization of the lysosomes and late endosomes in living cells.

DND-167 is used as a pH indicator. It has weak fluorescence at neutral pH but become much brighter at the blue region of spectra at pH ~3.0. An excitation/emission maxima of the dye are 370 and 425 nm, respectively.

The dye is supplied as a 1 mM solution in DMSO.

General properties

Appearance: yellowish solution
Molecular weight: 376.49
Molecular formula: C6H11N3O3
IUPAC name: 4-[[10-(morpholin-4-ylmethyl)anthracen-9-yl]methyl]morpholine
Solubility: good in dichloromethane, limited in DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
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