DND-167, blue fluorescent pH indicator
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 18410
/ 1 mM solution
|
20 x 50 uL
|
$380 | 1 days |
DND-167 (known as LysoSensor™ Blue DND-167, LysoView Blue) is a cell-permeable weak base that selectively accumulates in acidic vesicles after being protonated. The dye has a higher quantum yield in acidic environments with pKa at ~5.1, allowing visualization of the lysosomes and late endosomes in living cells.
DND-167 is used as a pH indicator. It has weak fluorescence at neutral pH but become much brighter at the blue region of spectra at pH ~3.0. An excitation/emission maxima of the dye are 370 and 425 nm, respectively.
The dye is supplied as a 1 mM solution in DMSO.
General properties
| Appearance: | yellowish solution |
| Molecular weight: | 376.49 |
| Molecular formula: | C6H11N3O3 |
| IUPAC name: | 4-[[10-(morpholin-4-ylmethyl)anthracen-9-yl]methyl]morpholine |
| Solubility: | good in dichloromethane, limited in DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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