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Cell biology reagents
Metabolic labeling
Ac4GlcNAz (N-Azidoacetylglucosamine-tetraacylated)

Ac4GlcNAz (N-Azidoacetylglucosamine-tetraacylated)

Azides Glycan labeling Click chemistry Copper-free click chemistry

Cat. #	Quantity	Price	Lead time
3662-5mg	5 mg	$129.00	in stock
3662-25mg	25 mg	$240.00	in stock
3662-100mg	100 mg	$630.00	in stock

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Tetraacetylated N-azidoacetylglucosamine (Ac4GlcNAz) is an azide-labeled monosaccharide widely used to study glycoproteins through in vivo metabolic incorporation followed by chemoselective ligation.

Ac4GlcNAz is a synthetic sugar that can penetrate cells, where it is recruited into natural metabolic pathways and displaces the endogenous N-acetylglucosamine (GlcNAc).

This results in the formation of glycoproteins bearing azide groups, which can be detected by click chemistry—a Cu(I)-catalyzed (CuAAC) or copper-free (SPAAC) reaction—using fluorescent alkynes/cycloalkynes or biotin-alkyne.

Concentrations of 25–75 μM are typically used for cell labeling; this range provides a convenient starting point for developing an experimental protocol.

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General properties

Appearance:	white solid
Molecular weight:	430.37
CAS number:	98924-81-3
Molecular formula:	C₁₆H₂₂N₄O₁₀
Solubility:	DMSO, DMF, DCM, THF, Chloroform
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.