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Ac4ManNAl (N-(4-pentynoyl)-mannosamine-tetraacylated)

Ac4ManNAl (N-(4-pentynoyl)-mannosamine-tetraacylated)

Alkynes Glycan labeling Click chemistry

Cat. #	Quantity	Price	Lead time
3431-5mg	5 mg	$129	in stock
3431-25mg	25 mg	$240	in stock
3431-100mg	100 mg	$630	in stock

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The tetraacetylated N-(4-pentynoyl)-mannosamine (Ac4ManNAl) is an alkyne-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4ManNAl is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-acetylmannosamine (ManNAc).

The resulting alkyne-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) click reaction with either fluorescent-labeled azides or biotin-azide.

Structure of Ac4ManNAl (N-(4-pentynoyl)-mannosamine-tetraacylated)

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General properties

Appearance:	white powder
Molecular weight:	427.41
CAS number:	935658-93-8
Molecular formula:	C₁₉H₂₅NO₁₀
IUPAC name:	2-deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-1,3,4,6-Tetraacetate-D-Mannopyranose
Solubility:	DMSO, DMF, DCM, THF, Chloroform
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.