Ac4ManNAz (N-Azidoacetylmannosamine-tetraacylated)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 3159-5mg | 5 mg |
$129
|
in stock | |
| 3159-25mg | 25 mg |
$240
|
in stock | |
| 3159-100mg | 100 mg |
$630
|
in stock |
The tetraacetylated N-Azidoacetyl-mannosamine (Ac4ManNAz) is an azide-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.
Ac4ManNAz is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylmannosamine (ManNAc).
The resulting azide-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) or copper-free (SPAAC) click reaction with either fluorescent-labeled alkynes/cycloalkynes or biotin-alkyne.
The recommended concentration for cell labeling is 25-75 μM, and this concentration range may be a starting point for an individual experiment setup.
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An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.General properties
| Appearance: | white solid |
| Molecular weight: | 430.37 |
| CAS number: | 361154-30-5 |
| Molecular formula: | C16H22N4O10 |
| Solubility: | Soluble to 100 mM in DMSO |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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