3-Maleimidopropionic acid NHS-ester

Cat. # Quantity Price Lead time
3419-100mg 100 mg –   in stock
3419-500mg 500 mg $110 in stock
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3-Maleimidopropionic acid N-hydroxysuccinimide (NHS) ester is a membrane-permeable, non-cleavable bifunctional crosslinker. It contains an amine-reactive succinimidyl ester and a thiol-reactive maleimide group.

The NHS residue can be attached to almost any primary or secondary amine group of proteins, peptides, or small molecule amines. The maleimide moiety provides easy attachment to proteins and peptides via SH-residues of cysteine and to other thiolated molecules, such as thiol-containing oligonucleotides.

This reagent is also used for in situ synthesis of chemically unstable azide-PEG4-maleimide.

General properties

Appearance: white crystals
Molecular weight: 266.21
CAS number: 55750-62-4
Molecular formula: C11H10N2O6
IUPAC name: N-(3-Maleimidopropionyloxy)succinimide
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
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