F-ara-EdU (2’-Deoxy-2’-fluoro-5-ethynyluridine)

Cat. # Quantity Price Lead time
3438-5mg 5 mg –   in stock
3438-25mg 25 mg $375 in stock
3438-100mg 100 mg $825 in stock
3438-500mg 500 mg please inquire in stock
Found better price? Let us know and we will propose the way forward!

F-ara-EdU (2’-deoxy-2’-fluoro-5-ethynyluridine) is a synthetic analog of thymidine used to study de novo DNA synthesis and cell proliferation. It is a less cytotoxic alternative for BrdU (5-Bromo-2’-deoxyuridine) and EdU (5-Ethynyl-2’-deoxyuridine).

F-ara-EdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. Metabolic incorporation of F-ara-EdU into DNA can be detected by copper-catalyzed click reaction with fluorescent or biotin-labeled azides.

In contrast to EdU, F-ara-EdU causes little or no cellular arrest or DNA synthesis inhibition. Therefore, F-ara-EdU is ideally suited for pulse-chase experiments aimed at birth-dating DNA in vivo and long-term cell survival estimation.

Customers also purchased with this product

AF 647 azide

Bright and photostable azide AF 647 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.

AF 488 azide

AF 488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.

Ascorbic acid

Ascorbic acid is a reducing agent converting copper(II) into a monovalent form that catalyzes the click reaction.

General properties

Appearance: off-white powder
Molecular weight: 270.22
CAS number: 95740-26-4
Molecular formula: C11H11FN2O5
Solubility: in water, DMSO, DMF
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.