BAPTA AM, calcium chelator

Cat. # Quantity Price Lead time
1891-5mg 5 mg $30 in stock
1891-25mg 25 mg $149 $105 in stock
Bulk inquiry
Found better price? Let us know and we will propose the way forward!

BAPTA AM is a membrane-permeable form of BAPTA, a highly selective calcium chelator. After loading into a cell, BAPTA AM is converted into BAPTA by cytoplasmic esterases. It is widely used for controlling the cytosolic calcium concentration (Kd = 0.11 μM), inhibiting voltage-gated potassium (Kv) channels, and other applications evaluating the role of intracellular calcium in cell signaling.

BAPTA AM can also be used as a calcium indicator since its absorption maximum changes after complexing with calcium (absorption max. of free/complexed is at 254/274 nm, emission max. of free/complexed is at 363/363 nm).

The commonly used concentration of BAPTA AM for cell signaling studies is 10-100 μM. Because AM esters have low water solubility, mild detergent (such as Pluronic® F-127) is necessary to facilitate loading into the cell.

BAPTA AM, calcium chelator, 1891-25mg
BAPTA AM, calcium chelator, 1891-25mg
BAPTA AM, calcium chelator, 1891-25mg
Structure of BAPTA AM, calcium chelator
Download in
ChemDraw format

Absorption and emission spectra of the Calcium ion-BAPTA complex

Absorption and emission spectra of the Calcium ion-BAPTA complex

Customers also purchased with this product

Laurdan (6-Dodecanoyl-2-dimethylaminonaphthalene)

Laurdan is a polarity-sensitive lipid membrane fluorescent probe. It is used for imaging lipid rafts and studying cell plasmatic membrane dynamics.

sulfo-Cyanine3 azide

Water-soluble sulfo-Cyanine3 dye azide for click chemistry labeling of sensitive molecules and intact biological objects.

LumiTracker® Mito Red CMXRos

Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.

General properties

Appearance: white to beige solid
Molecular weight: 764.69
CAS number: 126150-97-8
Molecular formula: C34H40N2O18
IUPAC name: N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-1,1'-bis[(acetyloxy)methyl] ester-glycine
Solubility: DMSO
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 274 (complex)
Emission maximum, nm: 372
Pluronic® F-127 is a registered trade mark of BASF.
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.