Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated)

Cat. # Quantity Price Lead time
4130-5mg 5 mg $129 in stock
4130-25mg 25 mg $240 in stock
4130-100mg 100 mg $630 in stock
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The tetraacetylated N-(4-pentynoyl)-glucosamine (Ac4GlcNAl) is an alkyne-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4GlcNAl is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-acetylglucosamine (GlcNAc).

The resulting alkyne-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) click reaction with either fluorescent-labeled azides or biotin-azide.

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General properties

Appearance: beige powder
Molecular weight: 427.41
CAS number: 1361993-37-4
Molecular formula: C19H25NO10
IUPAC name: 2-deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-2-deoxy-1,3,4,6-tetra-O-acetyl-D-glucopyranose
Solubility: DMSO, DMF, DCM, THF, chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
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