YO-TAP-1, green fluorescent nucleic acid stain

Cat. # Quantity Price Lead time
A1710 50 uL, 5 mM/DMSO $85 in stock
21710 200 uL, 5 mM/DMSO $320 in stock
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YO-TAP-1 (Oxazole Yellow Monomer, also known as YO-PRO®-1) is a green fluorescent carbocyanine monomeric dye. YO-TAP-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a significant fluorescence enhancement upon binding to dsDNA.

YO-TAP-1 has a bright fluorescence signal and low background. The dye is useful for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in microscopy. It may be used for monitoring of cell viability and apoptotic and dead cell detection in culture.

Absorption and emission spectra of YO-TAP-1 (DNA–dye complex)

Absorption and emission spectra of YO-TAP-1 (DNA–dye complex)

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General properties

Appearance: orange solution
Molecular weight: 629.32
CAS number: 152068-09-2
Molecular formula: C24H29I2N3O
IUPAC name: Quinolinium, 4-((3-methyl-2(3H)-benzoxazolylidene)methyl)-1-(3-(trimethylammonio)propyl)-, diiodide
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 491
Emission maximum, nm: 508
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