Cyanine7 tetrazine

Cat. # Quantity Price Lead time
150E0 1 mg $110.00 in stock
250E0 5 mg $290.00 in stock
450E0 25 mg $690.00 in stock
550E0 50 mg $1270.00 in stock
650E0 100 mg $1990.00 in stock

TCO ligation is a reaction that takes place between a tetrazine and a strained olefin, such as trans-cyclooctene.

This tetrazine bears a fragment of near infrared dye, Cyanine7. This NIR fluorophore is especially useful for in vivo imaging.

Absorption and emission spectra of Cyanine7

Absorption and emission spectra of Cyanine7

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Cyanine5 tetrazine

Cyanine5 is a universal red emitting dye with a very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.

Cyanine7 DBCO

NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.
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Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

General properties

Appearance: dark colored solid
Mass spec M+ increment: 703.4
Molecular weight: 877.94
Molecular formula: C47H54N7F6OP
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
CF260: 0.022
CF280: 0.029
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