Alkyne-PEG3-maleimide

Cat. # Quantity Price Lead time
2344-100mg 100 mg $140.00 in stock
2344-1g 1 g $530.00 in stock

Polyethylene glycol derivatives with few units (in this case, 3 monomeric units) are excellent linkers for conjugation of biomolecules to run reactions in aqueous conditions and increase the hydrophilicity of the compounds resulting from conjugation.

Terminal alkynes readily react in Click Chemistry reactions with various azides in the presence of copper (I) salts, and maleimide derivatives react with thiols. This is especially relevant for proteins and peptides that contain free -SH groups.

Alkyne-PEG3-maleimide is a cross-linker that can be widely used in chemistry, biology, and related areas.

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Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.

Alkyne-PEG3-NHS ester

Bifunctional hyrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).
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Alkyne-PEG3-Iodide

PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and Click chemistry.
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General properties

Appearance: yellow oil
Molecular weight: 267.28
CAS number: 1351974-20-3
Molecular formula: C13H17NO5
IUPAC name: 1-(2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications
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