Alkyne-PEG3-COOH
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 1743-1g | 1 g |
$490.00
|
in stock | |
| 1743-5g | 5 g |
$980.00
|
in stock | |
| 1743-25g | 25 g |
please inquire
|
in stock |
Alkyne-PEG3-COOH is a bifunctional triethyleneglycol derivative bearing a carboxy group, and an alkyne moiety. The former can be activated with peptide coupling reagents like PyBOP or carbodiimides like EDC to form a stable amide linkage with amines. The alkyne group can be coupled with azides in a CuAAc reaction.
PEGs are hydrophilic linkers that are useful in the synthesis of water soluble conjugates.
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Azide-PEG3-Amine
A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)General properties
| Appearance: | colorless to yellow oil |
| Molecular weight: | 246.26 |
| CAS number: | 1415800-32-6 |
| Molecular formula: | C11H18O6 |
| IUPAC name: | 3,6,9,12-tetraoxapentadecyn-15-oic acid |
| Solubility: | good in most organic solvents and water |
| Quality control: | NMR 1H, GC-MS (95%, as Me ester) |
| Storage conditions: | Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product citations
- Petrov, R.A.; Mefedova, S.R.; Yamansarov, E.Y.; Maklakova, S.Y.; Grishin, D.A.; Lopatukhina, E.V.; Burenina, O.Y.; Lopukhov, A.V.; Kovalev, S.V.; Timchenko, Y.V.; Ondar, E.E.; Ivanenkov, Y.A.; Evteev, S.A.; Vaneev, A.N.; Timoshenko, R.V.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma. Molecular Pharmaceutics, 2021, 18(1), 461–468. doi: 10.1021/acs.molpharmaceut.0c00980
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