Azide-PEG3-Carboxylic acid

Cat. # Quantity Price Lead time
2558-1g 1 g $265.00 in stock
2558-5g 5 g $950.00 in stock

Azide-PEG3-Carboxylic acid is a bifunctional linker with terminal carboxyl and azido groups.

This molecule is hydrophilic and suitable for the synthesis of water-soluble conjugates.

The azide group can enter into [3+2]-dipolar cycloaddition reactions with biomolecules containing an alkyne moiety (Click Chemistry reactions), and the carboxyl group can be activated and react with various amines.

The repertoire of the synthesized bioconjugates can be very broad; for example, different antibody-drug conjugates (ADC) can be generated using this approach. Also, the conjugation of a PEG linker to a molecule can increase its stability and solubility in water, as well as reduce the immunogenicity.

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Alkyne-PEG3-amine

Alkyne PEG3 amine is a medium length heterobifunctional linker for the conjugation.

Alkyne-PEG3-COOH

Bifunctional linker with terminal alkyne function, and carboxylic acid moiety, CAS# 1415800-32-6.
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General properties

Appearance: colorless liquid
Molecular weight: 247.25
CAS number: 1056024-94-2
Molecular formula: C9H17N3O5
IUPAC name: 3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanoic acid
Solubility: good in water and most organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications
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