Sulfo-Cyanine5 carboxylic acid

Cat. # Quantity Price Lead time
13390 1 mg $110.00 in stock
23390 5 mg $290.00 in stock
43390 25 mg $690.00 in stock
53390 50 mg $1270.00 in stock
63390 100 mg $1990.00 in stock

Non-activated sulfo-Cyanine5 carboxylic acid, water soluble dye. This dye is highly hydrophilic and water-soluble. Non-sulfonated analog is available.

The fluorophore is an equivalent of Cy5® carboxylic acid.

For labeling applications consider using pre-activated sulfo-Cy5 NHS ester

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 absorbance and emission spectra

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Sulfo-Cyanine7 carboxylic acid

Sulfo-Cy7 carboxylic acid is a non-reactive fluorescent dye which can be used as a NIR (near infrared) marker.

General properties

Appearance: dark blue powder
Molecular weight: 664.76
CAS number: 1121756-16-8, 1144162-77-5
Molecular formula: C32H37N2NaO8S2
Solubility: Good in water, DMF, DMSO. Low in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download

Spectral properties

Excitation maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Product citations

  1. Cho, U.; Riordan, D.P.; Ciepla, P.; Kocherlakota, K.S.; Chen, J.K.; Harbury, P.B. Ultrasensitive optical imaging with lanthanide lumiphores. Nature Chemical Biology, 2018, 14(1), 15–21. doi: 10.1038/nchembio.2513
  2. Than, A.; Liang, K.; Xu, S.; Sun, L.; Duan, H.; Xi, F.; Xu, C.; Chen, P. Transdermal Delivery of Anti-Obesity Compounds to Subcutaneous Adipose Tissue with Polymeric Microneedle Patches. Small Methods, 2017, 1(11), 1700269. doi: 10.1002/smtd.201700269
  3. Summer, D.; Grossrubatscher, L.; Petrik, M.; Michalcikova, T.; Novy, Z.; Rangger, C.; Klingler, M.; von Guggenberg, E.; Haubner, R.; Kaeopookum, P.; Haas, H.; Decristoforo, C. Developing targeted hybrid imaging probes by chelator scaffolding. Bioconjugate Chemistry, 2017, 28(6), 1722–1733. doi: 10.1021/acs.bioconjchem.7b00182
  4. Hatai, J.; Motiei, L.; Margulies, D. Analyzing Amyloid Beta Aggregates with a Combinatorial Fluorescent Molecular Sensor. Journal of the American Chemical Society, 2017, 139(6), 2136–2139. doi: 10.1021/jacs.6b10809
  5. Schlegel, I.; Muñoz-Espí, R.; Renz, P.; Lieberwirth, I.; Floudas, G.; Suzuki, Y.; Crespy, D.; Landfester, K. Crystallinity Tunes Permeability of Polymer Nanocapsules. Macromolecules, 2017, 50(12), 4725–4732. doi: 10.1021/acs.macromol.7b00667
  6. Liu, M.; Richardson, R.R.; Mountford, S.J.; Zhang, L.; Tempone, M.H.; Herzog, H.; Holliday, N.D.; Thompson, P.E. Identification of a Cyanine-Dye Labelled Peptidic Ligand for Y1R and Y4R, based upon the Neuropeptide Y C-terminal analogue, BVD-15. Bioconjugate Chemistry, 2016, 27(9), 2166–2175. doi: 10.1021/acs.bioconjchem.6b00376
  7. Gao, P.; Hunter, A.J.; Summe, M.J.; Phillip, W.A. A Method for the Efficient Fabrication of Multifunctional Mosaic Membranes by Inkjet Printing. ACS Applied Materials & Interfaces, 2016, 8(30), 19772–19779. doi: 10.1021/acsami.6b06048
  8. Calver, C.F.; Liu, H.-W.; Cosa, G. Exploiting Conjugated Polyelectrolyte Photophysics towards Monitoring Real-Time Lipid Membrane-Surface Interaction Dynamics at the Single Particle Level. Langmuir, 2015, 31(43), 11842–11850. doi: 10.1021/acs.langmuir.5b00979
  9. Lee, S.J.; Shim, Y.H.; Oh, J.-S.; Jeong, Y.-I. Park, I.-K.; Lee, H.C. Folic-acid-conjugated pullulan/poly(DL-lactide-co-glycolide) graft copolymer nanoparticles for folate-receptor-mediated drug delivery. Nanoscale Research Letters, 2015, 10, 43. doi: 10.1186/s11671-014-0706-1
  10. Tucker, K.R.; Block, E.R.; Levitan, E.S. Action potentials and amphetamine release antipsychotic drug from dopamine neuron synaptic VMAT vesicles. Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112(32), E4485–E4494. doi: 10.1073/pnas.1503766112
  11. Lin, W.; Liu, J.; Jeffries, C.; Yang, L.; Lu, Y.; Lee, R.E.; Chen, T. Development of BODIPY FL Vindoline as a Novel and High-Affinity Pregnane X Receptor Fluorescent Probe. Bioconjugate Chemistry, 2014, 25(9), 1664-1677. doi: 10.1021/bc5002856
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