Sulfo-Cyanine5 carboxylic acid

Cat. # Quantity Price Lead time
13390 1 mg $110.00 5 days
23390 5 mg $210.00 in stock
43390 25 mg $410.00 in stock
53390 50 mg $695.00 in stock
63390 100 mg $1190.00 in stock

Non-activated sulfo-Cyanine5 carboxylic acid, water soluble dye. This dye is highly hydrophilic and water-soluble. Non-sulfonated analog is available.

The fluorophore is an equivalent of Cy5® carboxylic acid.

For labeling applications consider using pre-activated sulfo-Cy5 NHS ester

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 absorbance and emission spectra

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Water soluble cyanine dye with bright fluorescence, and high extinction coefficient. Contains an amino group for the conjugation with electrophiles, and enzymatic transamination labeling.

General properties

Appearance: dark blue powder
Molecular weight: 680,87
CAS number: 1144107-82-3 (potassium salt), 1121756-16-8 (inner salt), 2098639-31-5 (sodium salt)
Molecular formula: C32H37N2KO8S2
Solubility: Well soluble in water, DMF, DMSO (0.35 M = 240 g/L). Practically insoluble in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Product citations

  1. Novoselova, M.V.; Abakumova, T.O.; Khlebtsov, B.N.; Zatsepin, T.S.; Lazareva, E.N.; Tuchin, V.V.; Zharov, V.P.; Gorin, D.A.; Galanzha, E.I. Optical clearing for photoacoustic lympho- and angiography beyond conventional depth limit in vivo. Photoacoustics, 2020, 20, 100186. doi: 10.1016/j.pacs.2020.100186
  2. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  3. Pfister, J.; Summer, D.; Petrik, M.; Khoylou, M.; Lichius, A.; Kaeopookum, P.; Kochinke, L.; Orasch, T.; Haas, H.; Decristoforo, C. Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores. Biomolecules, 2020, 10, 168. doi: 10.3390/biom10020168
  4. He, X.; Yuan, Z.; Kao, W.; Miller, D.; Li, S.K.; Park, Y.C. Size-Exclusive Nanoporous Biodegradable PLGA Capsules for Drug Delivery Implants and In Vivo Stability in the Posterior Segment. ACS Applied Bio Materials, 2020, 3(3), 1722–1729. doi: 10.1021/acsabm.0c00027
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