TAMRA alkyne, 6-isomer

Cat. # Quantity Price Lead time
A81B0 1 mg –   in stock
B81B0 5 mg $260 in stock
C81B0 10 mg $325 in stock
D81B0 25 mg $410 in stock
E81B0 50 mg $695 in stock
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Tetramethylrhodamine (TAMRA) alkyne, pure 6-isomer. TAMRA is a popular dye that is used in qPCR and other applications. It forms a FRET pair with FAM (serving as an acceptor).

This product is a terminal alkyne for copper-catalyzed click chemistry. It can be conjugated with azide groups using CuAAC reaction.

Absorption and emission spectra of 6-TAMRA

Absorption and emission spectra of 6-TAMRA

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General properties

Appearance: dark colored solid
Mass spec M+ increment: 467.2
Molecular weight: 467.52
CAS number: 1352649-44-5
Molecular formula: C28H25N3O4
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.34
CF280: 0.17

Product citations

  1. Rink, W.M.; Thomas, F. Decoration of Coiled-Coil Peptides with N-Cysteine Peptide Thioesters As Cyclic Peptide Precursors Using Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) Click Reaction. Organic Letters, 2018, 20(23), 7493–7497. doi: 10.1021/acs.orglett.8b03261
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