Phosphate CPG 500 v2

Cat. # Quantity Price Lead time
17860 100 mg $40 in stock
47860 1 g $170 in stock
Found better price? Let us know and we will propose the way forward!

Phosphate CPG 500 v2 allows direct preparation of oligonucleotides with a 3’-phosphate group.

The sulfone linker is one of the linkers employed for the preparation of oligonucleotides, it releases the oligonucleotide 3’-phosphate by β-elimination upon ammonolysis.

Available in different pore sizes, Phosphate CPG 500 v2 with pore size of 500 Å is recommended for the synthesis of oligonucleotides up to 30 bases.

For synthesis longer oligonucleotides 1000 Å CPG can be used.

Usage

Coupling: identical to normal protected nucleoside support.

Deprotection: identical to protected nucleobases.

Customers also purchased with this product

MGB CPG 1000

MGB CPG 1000 for the synthesis of oligonucleotides bearing dihydropyrroloindole tripeptide for binding to the DNA minor groove.

Alkyne amidite, hydroxyprolinol

Acetylenic amidite for the incorporation of acetylene groups into oligos.

Phosphate CPG 500 solid support

CPG solid support for the synthesis of 3'-phosphorylated oligonucleotides.

General properties

Appearance: slightly yellow beads
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 50-80
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: identical to protected nucleobases
Deprotection conditions: identical to protected nucleobases
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.