DusQ® 3 CPG 500

CPG modifier solid supports DusQ® 3

Cat. #	Quantity	Price	Lead time	Buy this product
1618-100mg	100 mg	–	in stock
1618-1g	1 g	$990	in stock

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DusQ^® 3 is a dark quencher for far red and near infrared fluorophores, especially suitable for Cyanine5.5.

The dye can be attached to 3′-terminus of oligonucleotides by means of automated solid phase synthesis using this support. The dye is sensitive to nucleophilic reagents, and therefore must be carefully deprotected. We recommend the use of ultramild, phenoxyacetyl protected monomers. As an alternative, post-synthetic labeling using NHS ester of the quencher can be used.

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Absorption spectrum of DusQ 3

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FAM phosphoramidite, 6-isomer

FAM (fluorescein) phosphoramidite 6-isomer, is a widely used reagent in nucleic acid chemistry for labeling oligonucleotides. It is derived from the single pure isomer of 6-carboxyfluorescein and separated from amidite linkage via C6 aminohexanol spacer.

FAM phosphoramidite, 5-isomer

Single isomer 5-FAM phosphoramidite for the synthesis of modified oligonucleotides.

General properties

Appearance:	dark blue beads
Quality control:	¹H NMR of bound reagent, coupling testing with HPLC-MS
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	657
ε, L⋅mol⁻¹⋅cm⁻¹:	45500

Oligo synthesis details

Pore size, Å:	500
Typical loading, umol/g:	50-80
Coupling conditions:	standard, ultramild phosphoramidites
Cleavage conditions:	2 h / rt, 30% aq. ammonia (ultramild protective groups)

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.