Biotin-11-dUTP

Triphosphates

Cat. #	Quantity	Price	Lead time
1553-250nmol	250 nmol	$140	20 days
1553-500nmol	500 nmol	$235	in stock
1553-1umol	1 umol	$360	20 days
1553-5umol	5 umol	please inquire	in stock

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Biotinylated deoxyuridine triphosphate (dUTP) can be used for DNA labeling using various methods, including Nick-translation and 3’-terminal non-radioactive labeling. Generated probes can be used in various hybridization experiments such as Southern blot, Northern blot, dot blot, or FISH. Biotin-labeled probes are detected with horseradish peroxidase-conjugated streptavidin or other biomolecule conjugates binding biotin.

«11» in the compound name indicates the length of the linker between dUTP and biotin; this linker increases the efficiency of labeled dUTP incorporation into DNA and interaction of biotin with specific proteins such as avidin/streptavidin or anti-biotin antibodies.

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General properties

Appearance:	colorless solid
Molecular weight:	878.54
Molecular formula:	C₂₈H₄₀N₆Li₃O₁₇P₃S
IUPAC name:	((2R,3S,5R)-5-(2,4-dioxo-5-(3-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)prop-1-yn-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate
Solubility:	soluble in water
Quality control:	HPLC-MS (95%), testing in enzymatic reaction
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid excessive freeze-thaw cycles.
MSDS:	Download
	Product specifications

Product citations

Krasikova, A.; Kulikova, T.; Schelkunov, M.; Makarova, N.; Fedotova, A.; Plotnikov, V.; Berngardt, V.; Maslova, A.; Fedorov, A. The First Chicken Oocyte Nucleus Whole Transcriptomic Profile Defines the Spectrum of Maternal MRNA and Non-Coding RNA Genes Transcribed by the Lampbrush Chromosomes. Nucleic Acids Research, 2024, 52(21), 12850–12877. doi: 10.1093/nar/gkae941
Krasikova, A.; Kulikova, T.; Rodriguez Ramos, J. S.; Maslova, A. Assignment of the Somatic A/B Compartments to Chromatin Domains in Giant Transcriptionally Active Lampbrush Chromosomes. Epigenetics & Chromatin, 2023, 16(1), 24. doi: 10.1186/s13072-023-00499-2

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.