Alkyne dT phosphoramidite

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Product discontinued in favor of new version of Alkyne dT phosphoramidite.

Alkyne dT phosphoramidite is used for the synthesis of oligonucleotides containing an internal alkyne modification attached to the uridine 5-position. The alkyne group can be subsequently modified by various azides using copper-catalyzed Click chemistry.

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DusQ2 phosphoramidite

DusQ2 is a black quencher dye phosphoramidite for the synthesis of dual labeled probes. Useful for HEX, JOE, ROX, Cyanine5, and other dyes.
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Cyanine5.5 azide

Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.

General properties

Appearance: white solid
Molecular weight: 935.01
Molecular formula: C50H59N6O10P
Solubility: good in THF, DCM, acetonitrile
Quality control: NMR 1H, HPLC-MS (90+%), functional testing in oligo synthesis
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Oligo synthesis details

Coupling conditions: 6 min. coupling time; 45 sec. oxidation time
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases
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