Sulfo-Cyanine7.5 is a heptamethyne cyanine dye for the near infrared region of the spectrum, which is very hydrophilic, and water soluble. The fluorophore resembles ICG (indocyanine green) that has a long history of in vivo use, and is even approved for human angiography. However, compared to ICG, sulfo-Cyanine7.5 has a significantly improved fluorescence quantum yield due to the rugged polymethine chain reinforced with trimethylene bridge.
Sulfo-Cyanine7.5 is available as a number of reactive derivatives. This azide can be used for the easy labeling of various biomolecules by copper-catalyzed or copper free Click chemistry.
Sulfo-Cyanine7.5 is a near infrared fluorophore similar to indocyanine green (ICG), but possessing higher fluorescence quantum yield. The dye is very hydrophilic and water soluble. The reagent is very useful for the labeling of biomolecules for in vivo imaging. This is an alkyne for copper catalyzed Click chemistry.
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Cyclooctyne derivative of fluorescein (FAM) for copper free Click chemistry reaction with azides. Contains pure 6-isomer of fluorescein.
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General properties
Appearance:
dark colored solid
Mass spec M+ increment:
1050.3
Molecular weight:
1165.51
Molecular formula:
C48H51N6K3O13S4
Solubility:
good in water, DMSO, DMF
Quality control:
NMR 1H, HPLC-MS (95%)
Storage conditions:
Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.