Universal CPG type II, 500A

CPG modifier solid supports Oligonucleotide synthesis

Cat. #	Quantity	Price	Lead time
3219-1g	1 g	$45.00	in stock
3219-10g	10 g	$410.00	in stock
3219-100g	100 g	please inquire	21 days

Found better price? Let us know and we will propose the way forward!

The Universal CPG type II, 500 Å is used for oligonucleotides synthesis to increase rate of dephosphorylation of the 3' end oligonucleotide during deblocking due to a rigid bicyclic molecule on the support.

The Universal CPG type II, 500 Å is suitable for use in harsh conditions and makes cleavage and deprotection with anhydrous ammonia gas-phase, ammonium hydroxide/methylamine (AMA) mixture or other basic reagents faster compared to universal Controlled Pore Glass (CPG) supports. Pore size of 500 Å is recommended for the synthesis of oligonucleotides up to 50 bases. For oligos up to 120 bases universal support 1000 Å or 1400 Å can be used.

Structure of Universal CPG type II, 500A

Download in
ChemDraw format

Customers also purchased with this product

DusQ® 2 CPG 500

Controlled pore glass (CPG) 500 modified support for the synthesis of oligonucleotides wit…

TFA-amino modifier CPG 500

TFA-amino modifier CPG for oligo synthesis. 500 Å, high load controlled pore glass.…

ROX azide, 5-isomer

Azide derivative of ROX (Rhodamine X, Rhodamine 101) dye for biomolecule labeling via clic…

Cyanine5 azide

Cyanine5 azide is a reagent for click chemistry labeling with Cyanine5, a popular fluoresc…

JOE phosphoramidite, 5-isomer

JOE phosphoramidite is a xanthene dye phosphoramidite used in oligo synthesis. Its absorpt…

Universal CPG type I, 500A

This universal support is intended for the automated synthesis of all types of oligonucleo…

Inosine (dI) phosphoramidite

Dimethoxytrityl deoxyinosine (Dmt-dI) phosphoramidite for the synthesis of modified DNA ol…

3'-Azido-modifier CPG 1000A

Controlled pore glass solid support for DNA/RNA synthesis with azide modification (pore si…

DMS(O)MT aminolink C6

An amidite for the introduction of amino group for oligonucleotide synthesis.…

HEX azide, 6-isomer

Azide of green-yellow emitting HEX dye for conjugation with oligonucleotides via [3+2]-dip…

SIMA azide, 6-isomer

Azide of green-yellow emitting dye SIMA for conjugation with oligonucleotides via [3+2]-di…

DusQ® 21 NHS ester

Amino-reactive NHS ester with quencher for the conjugation with amines-containing molecule…

General properties

Appearance:	white powder
Quality control:	loading measurement, functional testing in oligo synthesis.
Storage conditions:	24 months after receival at −20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

Oligo synthesis details

Pore size, Å:	500
Typical loading, umol/g:	50−80
Coupling conditions:	standard conditions for universal CPG
Cleavage conditions:	2 hours at 80 °C or 8 hours at 55 °C using concentrated ammonia; 15 minutes at 65 °C using AMA mixture, ammonium hydroxide- 40% methylamine (1:1)
Deprotection conditions:	identical to protected nucleobases

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.