Cyanine5.5 azide

Cat. # Quantity Price Lead time
14030 100 uL, 10 mM/DMSO $110.00 5 days
34030 500 uL, 10 mM/DMSO $210.00 in stock
44030 1 mL, 10 mM/DMSO $410.00 in stock
A4030 1 mg $110.00 in stock
B4030 5 mg $210.00 in stock
C4030 10 mg $310.00 in stock
D4030 25 mg $410.00 in stock
E4030 50 mg $695.00 in stock

This Cyanine5.5 labeling reagent is a dye azide for Click Chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5® and DyLight 680.

Cy5.5 absorbance and emission spectra

Cy5.5 absorbance and emission spectra

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Ascorbic acid for the reduction of Cu(II)-TBTA complex.

Cyanine5 DBCO

Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper-free click chemistry.

General properties

Appearance: dark blue powder / solution
Molecular weight: 701.34
Molecular formula: C43H49ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (1.6 uM, 1.2 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Binkhathlan, Z.; Ali, R.; Qamar, W.; Al-Lawati, H.; Lavasanifar, A. Pharmacokinetic and Tissue Distribution of Orally Administered Cyclosporine A-Loaded poly(ethylene oxide)-block-Poly(ε-caprolactone) Micelles versus Sandimmune® in Rats. Pharmaceutical Research, 2021, 38(1), 51–65. doi: 10.1007/s11095-021-02990-5
  2. Bobrin, V.A.; Lin, Y.; He, J.; Qi, Y.; Gu, W.; Monteiro, M.J. Therapeutic Delivery of Polymeric Tadpole Nanostructures with High Selectivity to Triple Negative Breast Cancer Cells. Biomacromolecules, 2020, 21(11), 4457–4468. doi: 10.1021/acs.biomac.0c00302
  3. Yuan, M.; Chen, X.; Sun, Y.; Jiang, L.; Xia, Z:; Ye, K.; Jiang, H.; Yang, B.; Ying, M.; Cao, J.; He, Q. ZDHHC12-mediated claudin-3 S-palmitoylation determines ovarian cancer progression. Acta Pharmaceutica Sinica B, 2020, 10(8), 1426–1439. doi: 10.1016/j.apsb.2020.03.008
  4. Hellyer, S.D.; Aggarwal, S.; Chen, A.N.; Leach, K.; Lapinsky, D.J.; Gregory, K.J. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. ACS Chemical Neuroscience, 2020, 11(11), 1597–1609. doi: 10.1021/acschemneuro.0c00009
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