Alkyne maleimide
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 41780 | 25 mg | $95 | in stock | |
| 51780 | 50 mg | $175 | in stock | |
| 61780 | 100 mg | $200 | in stock |
Alkyne maleimide is a bifunctional linker reagent which allows to attach terminal alkyne to various thiol-containing molecules, such as proteins containing cysteine residues. The alkyne moiety can be then conjugated with various azides via copper-catalyzed сlick chemistry reaction.
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BDP® 630/650 amine
BDP 630/650 is a far red emitting fluorophore for Cyanine5 channel. This fluorophore is based on BDP (borondipyrromethene) core, which provides high quantum yield and photostability. This is an amine derivative of this dye.
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Ascorbic acid
Ascorbic acid is a reducing agent converting copper(II) into a monovalent form that catalyzes the click reaction.General properties
| Appearance: | colorless solid |
| Mass spec M+ increment: | 234.1 |
| Molecular weight: | 234.25 |
| Molecular formula: | C12H14N2O3 |
| Solubility: | good in DMSO, DMF, alcohols, limited in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product citations
- Hulce, K.R.; Jaishankar, P.; Lee, G.M.; Bohn, M.-F.; Connelly, E.J.; Wucherer, K.; Ongpipattanakul, C.; Volk, R.F.; Chuo, S.-W.; Arkin, M.R.; Renslo, A.R.; Craik, C.S. Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine. Cell Chemical Biology, 2022, 29(5), 785-798.e19. doi: 10.1016/j.chembiol.2022.03.007
- Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, 2021, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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