sulfo-Cyanine3 alkyne
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A13B0 | 1 mg | $125 | in stock | |
| B13B0 | 5 mg | $325 | in stock | |
| C13B0 | 10 mg |
$470
|
in stock | |
| D13B0 | 25 mg |
$850
|
in stock | |
| E13B0 | 50 mg |
$1490
|
in stock | |
| F13B0 | 100 mg |
$1990
|
in stock |
A water-soluble alkyne dye for copper-catalyzed click chemistry, an analog of Cy3® alkyne.
sulfo-Cyanine3 is a fluorophore compatible with a wide range of fluorescent scanners, imagers, microscopes, and other instrumentation. It is a bright and photostable dye, which is also easily detected in gels by the naked eye in low amounts (<1 nmol).
Absorbance and emission spectra of sulfo-Cyanine3
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AF 343 (Coumarin) X azide
AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.BTTAA ligand
BTTAA is the newest generation of water-soluble ligands for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that dramatically accelerates reaction rates and suppresses cell cytotoxicity.Biotin alkyne
Biotin alkyne is a reactive affinity label which can be attached to biomolecules via click reaction.General properties
| Appearance: | dark red powder |
| Mass spec M+ increment: | 653.2 |
| Molecular weight: | 691.90 |
| CAS number: | 2055138-87-7 (inner salt); 2055138-88-8 (sodium salt) |
| Molecular formula: | C33H38KN3O7S2 |
| Solubility: | soluble in water (0.57 M = 40 g/L), DMSO, DMF |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 548 |
| ε, L⋅mol−1⋅cm−1: | 162000 |
| Emission maximum, nm: | 563 |
| Fluorescence quantum yield: | 0.1 |
| CF260: | 0.03 |
| CF280: | 0.06 |
Product citations
- Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
- Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a "multiple gear" regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
- Guarin, M.; Ny, A.; De Croze, N.; Maes, J.; Léonard, M.; Annaert, P.; de Witte, P. A. M. Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals, 2021, 14(6), 576. doi: 10.3390/ph14060576
- Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration. Scientific Reports, 2021, 11, 12229. doi: 10.1038/s41598-021-91612-6
Cy® is a trademark of GE Healthcare.
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