DusQ3 CPG 500

Cat. # Quantity Price Lead time
1618-1g 1 g $990.00 21 days

DusQ3 is a dark quencher for far red and near infrared fluorophores, especially suitable for Cyanine5.5.

The dye can be attached to 3'-terminus of oligonucleotides by means of automated solid phase synthesis using this support. The dye is sensitive to nucleophilic reagents, and therefore must be carefully deprotected. We recommend the use of ultramild, phenoxyacetyl protected monomers. As an alternative, post-synthetic labeling using NHS ester of the quencher can be used.

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Controlled pore glass (CPG) 500 solid support for synthesis of oligonucleotides with 3’-terminal DusQ1 quencher. Compatible with standard deblocking conditions.
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DusQ2 CPG 500

Controlled pore glass (CPG) 500 modified support for the synthesis of oligonucleotides with DusQ2 quencher at the 3’ end. Compatible with standard deblocking conditions.
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General properties

Appearance: dark blue beads
Quality control: 1H NMR of bound reagent, coupling testing with HPLC-MS
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 50-80
Coupling conditions: standard, ultramild phosphoramidites
Cleavage conditions: 2 h / rt, 30% aq. ammonia (ultramild protective groups)
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