DusQ 3 CPG 500

Cat. # Quantity Price Lead time
1618-100mg 100 mg –   in stock
1618-1g 1 g $990 in stock
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DusQ 3 is a dark quencher for far red and near infrared fluorophores, especially suitable for Cyanine5.5.

The dye can be attached to 3'-terminus of oligonucleotides by means of automated solid phase synthesis using this support. The dye is sensitive to nucleophilic reagents, and therefore must be carefully deprotected. We recommend the use of ultramild, phenoxyacetyl protected monomers. As an alternative, post-synthetic labeling using NHS ester of the quencher can be used.

Absorption spectrum of DusQ 3

Absorption spectrum of DusQ 3

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General properties

Appearance: dark blue beads
Quality control: 1H NMR of bound reagent, coupling testing with HPLC-MS
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 657
ε, L⋅mol−1⋅cm−1: 45500

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 50-80
Coupling conditions: standard, ultramild phosphoramidites
Cleavage conditions: 2 h / rt, 30% aq. ammonia (ultramild protective groups)
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